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10.1186/s13054-015-0967-9

http://scihub22266oqcxt.onion/10.1186/s13054-015-0967-9
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C4479224!4479224!26104045
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suck abstract from ncbi


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pmid26104045      Crit+Care 2015 ; 19 (1): ä
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  • Selective decontamination and antibiotic resistance in ICUs #MMPMID26104045
  • Plantinga NL; Bonten MJ
  • Crit Care 2015[]; 19 (1): ä PMID26104045show ga
  • Selective digestive decontamination (SDD) and selective oropharyngeal decontamination (SOD) have been associated with reduced mortality and lower ICU-acquired bacteremia and ventilator-associated pneumonia rates in areas with low levels of antibiotic resistance. However, the effect of selective decontamination (SDD/SOD) in areas where multidrug-resistant Gram-negative bacteria are endemic is less clear. It will be important to determine whether SDD/SOD improves patient outcome in such settings and how these measures affect the epidemiology of multidrug-resistant Gram-negative bacteria. Here we review the current evidence on the effects of SDD/SOD on antibiotic resistance development in individual ICU patients as well as the effect on ICU ecology, the latter including both ICU-level antibiotic resistance and antibiotic resistance development during long-term use of SDD/SOD.
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