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10.1093/annonc/mdv188 http://scihub22266oqcxt.onion/10.1093/annonc/mdv188 C4478974!4478974!25908604     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Ann+Oncol 2015 ; 26 (7): 1504-10 Nephropedia Template TP {{tp|p=25908604|t=2015. Titration of signalling output: insights into clinical combinations of MEK and AKT inhibitors |pdf=|usr=}}{{25908604}} gab.com Text Titration of signalling output: insights into clinical combinations of MEK and AKT inhibitors JO: Ann Oncol http://www.kidney.de/pget.php?&tw=1&pmid=25908604 #FOAvip Our results show that sub-optimal inhibition of MEK in combination with AKT is less efficient in inhibiting cellular growth compared to completely inhibiting MEK and AKT alone. The results also show that KRAS mutant cells are more sensitive to a combination of MEK and AKT inhibitors compared to BRAF and PIK3CA mutant cells. Both these findings have clinical implications. Twit Text FOAVip Titration of signalling output: insights into clinical combinations of MEK and AKT inhibitors ????Ann Oncol http://www.kidney.de/pget.php?&tw=1&pmid=25908604 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25908604 #FOAvip English Wikipedia <ref>{{Cite pmid|25908604}}</ref> Titration of signalling output: insights into clinical combinations of MEK and AKT inhibitors #MMPMID25908604 Stewart A; Thavasu P; de Bono JS; Banerji U Ann Oncol 2015[Jul]; 26 (7): 1504-10 PMID25908604show ga Our results show that sub-optimal inhibition of MEK in combination with AKT is less efficient in inhibiting cellular growth compared to completely inhibiting MEK and AKT alone. The results also show that KRAS mutant cells are more sensitive to a combination of MEK and AKT inhibitors compared to BRAF and PIK3CA mutant cells. Both these findings have clinical implications. äTitration of signalling output: insights into clinical combinations of(epmc).pdf DeepDyve Pubget Overpricing