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10.1186/s13578-015-0019-9 http://scihub22266oqcxt.onion/10.1186/s13578-015-0019-9 C4478642!4478642!26110047     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Biosci 2015 ; 5 (ä): ä Nephropedia Template TP {{tp|p=26110047|t=2015. Apoptotic cell-linked immunoregulation: implications for promoting immune tolerance in transplantation |pdf=|usr=}}{{26110047}} gab.com Text Apoptotic cell-linked immunoregulation: implications for promoting immune tolerance in transplantation JO: Cell Biosci http://www.kidney.de/pget.php?&tw=1&pmid=26110047 #FOAvip The induction of alloantigen-specific immune tolerance is the ?Holy-Grail? in transplantation. Although it had been previously demonstrated that transient depletion of T cells through apoptosis could lead to long-term immune tolerance, the underlying mechanism responsible for this tolerance induction and maintenance was unknown. In this short article, a novel mechanism for long-term immune tolerance via transient T cell apoptosis will be discussed, based on our recent findings in a CD3-specific antibody treatment-induced immune tolerance mouse model. Transforming growth factor-?, which is produced by immature dendritic cells whilst they phagocytose apoptotic T cells and by macrophages, plays an important role in initiating long-term immune tolerance. A possible model of how allospecific-immune tolerance can be induced in order to prevent allograft rejection in transplantation will be also proposed. Twit Text FOAVip Apoptotic cell-linked immunoregulation: implications for promoting immune tolerance in transplantation ????Cell Biosci http://www.kidney.de/pget.php?&tw=1&pmid=26110047 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26110047 #FOAvip English Wikipedia <ref>{{Cite pmid|26110047}}</ref> Apoptotic cell-linked immunoregulation: implications for promoting immune tolerance in transplantation #MMPMID26110047 Kuang R; Perruche S; Chen W Cell Biosci 2015[]; 5 (ä): ä PMID26110047show ga The induction of alloantigen-specific immune tolerance is the ?Holy-Grail? in transplantation. Although it had been previously demonstrated that transient depletion of T cells through apoptosis could lead to long-term immune tolerance, the underlying mechanism responsible for this tolerance induction and maintenance was unknown. In this short article, a novel mechanism for long-term immune tolerance via transient T cell apoptosis will be discussed, based on our recent findings in a CD3-specific antibody treatment-induced immune tolerance mouse model. Transforming growth factor-?, which is produced by immature dendritic cells whilst they phagocytose apoptotic T cells and by macrophages, plays an important role in initiating long-term immune tolerance. A possible model of how allospecific-immune tolerance can be induced in order to prevent allograft rejection in transplantation will be also proposed. äApoptotic cell-linked immunoregulation: implications for promoting imm(epmc).pdf DeepDyve Pubget Overpricing