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10.3748/wjg.v21.i23.7134 http://scihub22266oqcxt.onion/10.3748/wjg.v21.i23.7134 C4476874!4476874!26109799     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       World+J+Gastroenterol 2015 ; 21 (23): 7134-41 Nephropedia Template TP {{tp|p=26109799|t=2015. Review of a challenging clinical issue: Intrahepatic cholestasis of pregnancy |pdf=|usr=}}{{26109799}} gab.com Text Review of a challenging clinical issue: Intrahepatic cholestasis of pregnancy JO: World J Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=26109799 #FOAvip Intrahepatic cholestasis of pregnancy (ICP) is a reversible pregnancy-specific cholestatic condition characterized by pruritus, elevated liver enzymes, and increased serum bile acids. It commences usually in the late second or third trimester, and quickly resolves after delivery. The incidence is higher in South American and Scandinavian countries (9.2%-15.6% and 1.5%, respectively) than in Europe (0.1%-0.2%). The etiology is multifactorial where genetic, endocrine, and environmental factors interact. Maternal outcome is usually benign, whereas fetal complications such as preterm labor, meconium staining, fetal distress, and sudden intrauterine fetal demise not infrequently lead to considerable perinatal morbidity and mortality. Ursodeoxycholic acid is shown to be the most efficient therapeutic agent with proven safety and efficacy. Management of ICP consists of careful monitoring of maternal hepatic function tests and serum bile acid levels in addition to the assessment of fetal well-being and timely delivery after completion of fetal pulmonary maturity. This review focuses on the current concepts about ICP based on recent literature data and presents an update regarding the diagnosis and management of this challenging issue. Twit Text FOAVip Review of a challenging clinical issue: Intrahepatic cholestasis of pregnancy ????World J Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=26109799 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26109799 #FOAvip English Wikipedia <ref>{{Cite pmid|26109799}}</ref> Review of a challenging clinical issue: Intrahepatic cholestasis of pregnancy #MMPMID26109799 Ozkan S; Ceylan Y; Ozkan OV; Yildirim S World J Gastroenterol 2015[Jun]; 21 (23): 7134-41 PMID26109799show ga Intrahepatic cholestasis of pregnancy (ICP) is a reversible pregnancy-specific cholestatic condition characterized by pruritus, elevated liver enzymes, and increased serum bile acids. It commences usually in the late second or third trimester, and quickly resolves after delivery. The incidence is higher in South American and Scandinavian countries (9.2%-15.6% and 1.5%, respectively) than in Europe (0.1%-0.2%). The etiology is multifactorial where genetic, endocrine, and environmental factors interact. Maternal outcome is usually benign, whereas fetal complications such as preterm labor, meconium staining, fetal distress, and sudden intrauterine fetal demise not infrequently lead to considerable perinatal morbidity and mortality. Ursodeoxycholic acid is shown to be the most efficient therapeutic agent with proven safety and efficacy. Management of ICP consists of careful monitoring of maternal hepatic function tests and serum bile acid levels in addition to the assessment of fetal well-being and timely delivery after completion of fetal pulmonary maturity. This review focuses on the current concepts about ICP based on recent literature data and presents an update regarding the diagnosis and management of this challenging issue. äReview of a challenging clinical issue: Intrahepatic cholestasis of pr(epmc).pdf DeepDyve Pubget Overpricing