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10.2147/COPD.S54154 http://scihub22266oqcxt.onion/10.2147/COPD.S54154 C4476436!4476436 !26124657     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26124657 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Int+J+Chron+Obstruct+Pulmon+Dis 2015 ; 10 (ä): 1179-89 Nephropedia Template TP {{tp|p=26124657 |t=2015. Profile of a fixed-dose combination of tiotropium/olodaterol and its potential in the treatment of COPD |pdf=|usr=}}{{26124657 }} gab.com Text Profile of a fixed-dose combination of tiotropium/olodaterol and its potential in the treatment of COPD JO: Int J Chron Obstruct Pulmon Dis http://www.kidney.de/pget.php?&tw=1&pmid=26124657 #FOAvip Chronic obstructive pulmonary disease (COPD) is a progressive, debilitating disorder that results in frequent exacerbations and impacts quality of life. It represents a growing burden of health care cost, both from societal and economic perspectives. Short- and long-acting bronchodilators remain the mainstay of therapy in COPD patients. New fixed-dose combination inhalers with novel pharmacological combinations of long-acting ?2-agonists and muscarinic antagonists and delivered once-daily through a variety of devices are currently being developed and licensed for the treatment of COPD. There is mounting research suggesting that combining a fixed dose of a ?2-agonist and a muscarinic antagonist achieves better bronchodilation and clinical outcomes compared with either agent alone. These once-daily dosing inhalers are anticipated to impact favorably on patient preference and compliance. This review examines the fixed-dose combination of tiotropium bromide and olodaterol delivered by a Respimat(®) Soft Mist? inhaler at doses of 2.5/5 ?g and 5/5 ?g in moderate-to-very-severe COPD, and its potential role in COPD compared with other long-acting ?2-agonist with long-acting muscarinic antagonist combinations and delivery devices. Twit Text FOAVip Profile of a fixed-dose combination of tiotropium/olodaterol and its potential in the treatment of COPD ????Int J Chron Obstruct Pulmon Dis http://www.kidney.de/pget.php?&tw=1&pmid=26124657 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26124657 #FOAvip English Wikipedia <ref>{{Cite pmid|26124657 }}</ref> Profile of a fixed-dose combination of tiotropium/olodaterol and its potential in the treatment of COPD #MMPMID26124657 Muruganandan S ; Jayaram L Int J Chron Obstruct Pulmon Dis 2015[]; 10 (ä): 1179-89 PMID26124657 show ga Chronic obstructive pulmonary disease (COPD) is a progressive, debilitating disorder that results in frequent exacerbations and impacts quality of life. It represents a growing burden of health care cost, both from societal and economic perspectives. Short- and long-acting bronchodilators remain the mainstay of therapy in COPD patients. New fixed-dose combination inhalers with novel pharmacological combinations of long-acting ?2-agonists and muscarinic antagonists and delivered once-daily through a variety of devices are currently being developed and licensed for the treatment of COPD. There is mounting research suggesting that combining a fixed dose of a ?2-agonist and a muscarinic antagonist achieves better bronchodilation and clinical outcomes compared with either agent alone. These once-daily dosing inhalers are anticipated to impact favorably on patient preference and compliance. This review examines the fixed-dose combination of tiotropium bromide and olodaterol delivered by a Respimat(®) Soft Mist? inhaler at doses of 2.5/5 ?g and 5/5 ?g in moderate-to-very-severe COPD, and its potential role in COPD compared with other long-acting ?2-agonist with long-acting muscarinic antagonist combinations and delivery devices. |Administration, Inhalation [MESH] |Adrenergic beta-2 Receptor Agonists/*administration & dosage/adverse effects [MESH] |Benzoxazines/*administration & dosage/adverse effects [MESH] |Bronchodilator Agents/*administration & dosage/adverse effects [MESH] |Cholinergic Antagonists/*administration & dosage/adverse effects [MESH] |Drug Combinations [MESH] |Dry Powder Inhalers [MESH] |Exercise Tolerance/drug effects [MESH] |Humans [MESH] |Lung/*drug effects/physiopathology [MESH] |Pulmonary Disease, Chronic Obstructive/diagnosis/*drug therapy/physiopathology [MESH] |Quality of Life [MESH] |Recovery of Function [MESH] |Tiotropium Bromide/*administration & dosage/adverse effects [MESH]Profile of a fixed-dose combination of tiotropium/olodaterol and its p(epmc).pdf DeepDyve Pubget Overpricing