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2015 ; 2015
(ä): 847694
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English Wikipedia
Central Macular Thickness in Children with Myopia, Emmetropia, and Hyperopia: An
Optical Coherence Tomography Study
#MMPMID26167504
Yau GS
; Lee JW
; Woo TT
; Wong RL
; Wong IY
Biomed Res Int
2015[]; 2015
(ä): 847694
PMID26167504
show ga
PURPOSE: To investigate the central macular thickness (CMT) in myopic,
emmetropic, and hyperopic Chinese children using Optical Coherence Tomography.
METHODS: 168 right eyes of Chinese subjects aged 4-18 were divided into 3 groups
based on their postcycloplegic spherical equivalent: myopes (<-1.0 D); emmetropes
(?-1.0 to ?+1.0 D); and hyperopes (>+1.0 D) and the CMT was compared before/after
age adjustment. The CMT was correlated with age, axial length, and peripapillary
retinal nerve fibre layer (RNFL). RESULTS: The mean CMT was 274.9 ± 50.3 ?m and
the mean population age was 7.6 ± 3.3 years. The CMT was thickest in the myopes
(283.3 ± 57.3 ?m, n = 56), followed by the hyperopes (266.2 ± 55.31 ?m, n = 60)
and then emmetropes (259.8 ± 28.7 ?m, n = 52) (all P < 0.0001). When adjusted for
age, myopes had a thicker CMT than the other 2 groups (all P < 0.0001) but there
was no CMT difference between the emmetropes and hyperopes (P > 0.05). There was
no significant correlation between CMT with age, axial length, or peripapillary
RNFL (all P ? 0.2). CONCLUSION: Chinese children with myopia had a thicker CMT
than those with emmetropia or hyperopia. There was no correlation of the CMT with
age, axial length, or peripapillary RNFL thickness.