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10.1155/2015/847694

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suck abstract from ncbi


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pmid26167504
      Biomed+Res+Int 2015 ; 2015 (ä): 847694
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  • Central Macular Thickness in Children with Myopia, Emmetropia, and Hyperopia: An Optical Coherence Tomography Study #MMPMID26167504
  • Yau GS ; Lee JW ; Woo TT ; Wong RL ; Wong IY
  • Biomed Res Int 2015[]; 2015 (ä): 847694 PMID26167504 show ga
  • PURPOSE: To investigate the central macular thickness (CMT) in myopic, emmetropic, and hyperopic Chinese children using Optical Coherence Tomography. METHODS: 168 right eyes of Chinese subjects aged 4-18 were divided into 3 groups based on their postcycloplegic spherical equivalent: myopes (<-1.0 D); emmetropes (?-1.0 to ?+1.0 D); and hyperopes (>+1.0 D) and the CMT was compared before/after age adjustment. The CMT was correlated with age, axial length, and peripapillary retinal nerve fibre layer (RNFL). RESULTS: The mean CMT was 274.9 ± 50.3 ?m and the mean population age was 7.6 ± 3.3 years. The CMT was thickest in the myopes (283.3 ± 57.3 ?m, n = 56), followed by the hyperopes (266.2 ± 55.31 ?m, n = 60) and then emmetropes (259.8 ± 28.7 ?m, n = 52) (all P < 0.0001). When adjusted for age, myopes had a thicker CMT than the other 2 groups (all P < 0.0001) but there was no CMT difference between the emmetropes and hyperopes (P > 0.05). There was no significant correlation between CMT with age, axial length, or peripapillary RNFL (all P ? 0.2). CONCLUSION: Chinese children with myopia had a thicker CMT than those with emmetropia or hyperopia. There was no correlation of the CMT with age, axial length, or peripapillary RNFL thickness.
  • |*Emmetropia [MESH]
  • |Adolescent [MESH]
  • |Child [MESH]
  • |Child, Preschool [MESH]
  • |Cross-Sectional Studies [MESH]
  • |Female [MESH]
  • |Hong Kong/epidemiology [MESH]
  • |Humans [MESH]
  • |Hyperopia/epidemiology/*pathology [MESH]
  • |Macula Lutea/*pathology [MESH]
  • |Male [MESH]
  • |Myopia/epidemiology/*pathology [MESH]


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