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10.1016/j.arr.2013.01.005 http://scihub22266oqcxt.onion/10.1016/j.arr.2013.01.005 C4475282!4475282!23352928     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Ageing+Res+Rev 2013 ; 12 (3): 815-22 Nephropedia Template TP {{tp|p=23352928|t=2013. Reelin signaling in development, maintenance, and plasticity of neural networks |pdf=|usr=}}{{23352928}} gab.com Text Reelin signaling in development, maintenance, and plasticity of neural networks JO: Ageing Res Rev http://www.kidney.de/pget.php?&tw=1&pmid=23352928 #FOAvip The developing brain is formed through an orchestrated pattern of neuronal migration, leading to the formation of heterogeneous functional regions in the adult. Several proteins and pathways have been identified as mediators of developmental neuronal migration and cell positioning. However, these pathways do not cease to be functionally relevant after the embryonic and early postnatal period; instead, they switch from guiding cells, to guiding synapses. The outcome of synaptic guidance determines the strength and plasticity of neuronal networks by creating a scalable functional architecture that is sculpted by cues from the internal and external environment. Reelin is a multifunctional signal that coordinates cortical and subcortical morphogenesis during development and regulates structural plasticity in adulthood and ageing. Gain or loss of function in reelin or its receptors has the potential to influence synaptic strength and patterns of connectivity, with consequences for memory and cognition. The current review highlights similarities in the signaling cascades that modulate neuronal positioning during development, and synaptic plasticity in the adult, with a focus on reelin, a glycoprotein that is increasingly recognized for its dual role in the formation and maintenance of neural circuits. Twit Text FOAVip Reelin signaling in development, maintenance, and plasticity of neural networks ????Ageing Res Rev http://www.kidney.de/pget.php?&tw=1&pmid=23352928 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23352928 #FOAvip English Wikipedia <ref>{{Cite pmid|23352928}}</ref> Reelin signaling in development, maintenance, and plasticity of neural networks #MMPMID23352928 Stranahan AM; Erion JR; Wosiski-Kuhn M Ageing Res Rev 2013[Jun]; 12 (3): 815-22 PMID23352928show ga The developing brain is formed through an orchestrated pattern of neuronal migration, leading to the formation of heterogeneous functional regions in the adult. Several proteins and pathways have been identified as mediators of developmental neuronal migration and cell positioning. However, these pathways do not cease to be functionally relevant after the embryonic and early postnatal period; instead, they switch from guiding cells, to guiding synapses. The outcome of synaptic guidance determines the strength and plasticity of neuronal networks by creating a scalable functional architecture that is sculpted by cues from the internal and external environment. Reelin is a multifunctional signal that coordinates cortical and subcortical morphogenesis during development and regulates structural plasticity in adulthood and ageing. Gain or loss of function in reelin or its receptors has the potential to influence synaptic strength and patterns of connectivity, with consequences for memory and cognition. The current review highlights similarities in the signaling cascades that modulate neuronal positioning during development, and synaptic plasticity in the adult, with a focus on reelin, a glycoprotein that is increasingly recognized for its dual role in the formation and maintenance of neural circuits. äReelin signaling in development, maintenance, and plasticity of neural(epmc).pdf DeepDyve Pubget Overpricing