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2015 ; 13
(ä): 26
Nephropedia Template TP
gab.com Text
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English Wikipedia
Practice patterns and approach to kidney biopsy in lupus: a collaboration of the
Midwest Pediatric Nephrology Consortium and the Childhood Arthritis and
Rheumatology Research Alliance
#MMPMID26087651
Wenderfer SE
; Lane JC
; Shatat IF
; von Scheven E
; Ruth NM
Pediatr Rheumatol Online J
2015[Jun]; 13
(ä): 26
PMID26087651
show ga
BACKGROUND: There is no clear consensus regarding optimal indications or timing
of initial or repeat kidney biopsy in the management of pediatric systemic lupus
erythematosus (pSLE). METHODS: A web-based survey was designed to assess current
practice patterns among pediatric nephrologists and pediatric rheumatologists and
distributed to members of Midwest Pediatric Nephrology Consortium (MWPNC) and
Childhood Arthritis and Rheumatology Research Alliance (CARRA). RESULTS:
Respondents included 111 rheumatologists and 71 nephrologists from 65 and 34
centers, respectively. Numbers of years in sub-specialty practice were
comparable. Rheumatologists and nephrologists frequently collaborate in the care
of children with lupus nephritis (LN). More than 90% of respondents refer
patients to each either other after diagnosing LN. Over 60% describe shared
decision making regarding when to perform kidney biopsy and how to interpret
biopsy findings. Many pediatric nephrologists consider biopsy to be of higher
risk for complication in pSLE and alter their standard pre-or post-biopsy
management. CONCLUSIONS: It is uncommon for pediatric nephrologists to manage LN
without input from pediatric rheumatologists and vice versa. Consensus exists
between specialties in general, and practice differences that exist occur between
individual physicians rather than between specialties. A systematic approach to
biopsy may result in improved health related outcomes in pSLE.