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10.1016/j.nicl.2015.05.011 http://scihub22266oqcxt.onion/10.1016/j.nicl.2015.05.011 C4474365!4474365 !26106570     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26106570 &cmd=llinks): Failed to open stream: HTTP request failed! 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Dysfunction of ventrolateral prefrontal cortex underlying social anxiety disorder: A multi-channel NIRS study |pdf=|usr=}}{{26106570 }} gab.com Text Dysfunction of ventrolateral prefrontal cortex underlying social anxiety disorder: A multi-channel NIRS study JO: Neuroimage Clin http://www.kidney.de/pget.php?&tw=1&pmid=26106570 #FOAvip Social anxiety disorder (SAD) is characterized by strong fear and anxiety during social interactions. Although ventrolateral prefrontal cortex (VLPFC) activity in response to emotional stimuli is related to pathological anxiety, little is known about the relationship between VLPFC activity and social anxiety. This study aimed to investigate whether VLPFC activity was involved in SAD and whether VLPFC activity was related to the level of social anxiety. Twenty-four drug-naïve patients with SAD and 35 healthy controls underwent near-infrared spectroscopy (NIRS) scanning while performing a verbal fluency task (VFT). Results indicated that, compared to the healthy controls, the SAD patients exhibited smaller changes of oxygenated hemoglobin (oxy-Hb) concentrations in the VLPFC during the VFT. Furthermore, the right VLPFC activation was negatively correlated with social avoidance. In contrast to the latter, the healthy controls exhibited a positive correlation between changes of oxy-Hb concentrations in the bilateral VLPFC and social fear. Our findings provide evidence for VLPFC dysfunction in SAD, and indicate that the VLPFC dysfunction may contribute to the difference between normal and abnormal social anxiety. Twit Text FOAVip Dysfunction of ventrolateral prefrontal cortex underlying social anxiety disorder: A multi-channel NIRS study ????Neuroimage Clin http://www.kidney.de/pget.php?&tw=1&pmid=26106570 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26106570 #FOAvip English Wikipedia <ref>{{Cite pmid|26106570 }}</ref> Dysfunction of ventrolateral prefrontal cortex underlying social anxiety disorder: A multi-channel NIRS study #MMPMID26106570 Yokoyama C ; Kaiya H ; Kumano H ; Kinou M ; Umekage T ; Yasuda S ; Takei K ; Nishikawa M ; Sasaki T ; Nishimura Y ; Hara N ; Inoue K ; Kaneko Y ; Suzuki S ; Tanii H ; Okada M ; Okazaki Y Neuroimage Clin 2015[]; 8 (ä): 455-61 PMID26106570 show ga Social anxiety disorder (SAD) is characterized by strong fear and anxiety during social interactions. Although ventrolateral prefrontal cortex (VLPFC) activity in response to emotional stimuli is related to pathological anxiety, little is known about the relationship between VLPFC activity and social anxiety. This study aimed to investigate whether VLPFC activity was involved in SAD and whether VLPFC activity was related to the level of social anxiety. Twenty-four drug-naïve patients with SAD and 35 healthy controls underwent near-infrared spectroscopy (NIRS) scanning while performing a verbal fluency task (VFT). Results indicated that, compared to the healthy controls, the SAD patients exhibited smaller changes of oxygenated hemoglobin (oxy-Hb) concentrations in the VLPFC during the VFT. Furthermore, the right VLPFC activation was negatively correlated with social avoidance. In contrast to the latter, the healthy controls exhibited a positive correlation between changes of oxy-Hb concentrations in the bilateral VLPFC and social fear. Our findings provide evidence for VLPFC dysfunction in SAD, and indicate that the VLPFC dysfunction may contribute to the difference between normal and abnormal social anxiety. |*Oxyhemoglobins [MESH] |Adult [MESH] |Female [MESH] |Humans [MESH] |Male [MESH] |Middle Aged [MESH] |Phobic Disorders/*physiopathology [MESH] |Prefrontal Cortex/*physiopathology [MESH]Dysfunction of ventrolateral prefrontal cortex underlying social anxie(epmc).pdf DeepDyve Pubget Overpricing