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10.1016/j.cub.2012.08.002

http://scihub22266oqcxt.onion/10.1016/j.cub.2012.08.002
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C4472467!4472467!23058807
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suck abstract from ncbi

pmid23058807      Curr+Biol 2012 ; 22 (19): R849-51
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  • Cancer Biology: A New RING to Wnt Signaling #MMPMID23058807
  • Fearon ER; Spence JR
  • Curr Biol 2012[Oct]; 22 (19): R849-51 PMID23058807show ga
  • The ?-catenin-dependent Wnt signaling pathway has key roles in embryonic development and adult tissues, and mutations in the pathway underlie the development of colorectal and other cancers. Recent studies highlight the role of two transmembrane RING finger ubiquitin ligases in modulating Wnt signaling at the cell surface as well as the role of and implications for mutations of the RING finger proteins in cancer.
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