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10.1111/ajt.13133 http://scihub22266oqcxt.onion/10.1111/ajt.13133 C4472303!4472303!25766759     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Transplant 2015 ; 15 (5): 1349-59 Nephropedia Template TP {{tp|p=25766759|t=2015. Anti-Phospholipase A2 Receptor Antibodies in Recurrent Membranous Nephropathy |pdf=|usr=}}{{25766759}} gab.com Text Anti-Phospholipase A2 Receptor Antibodies in Recurrent Membranous Nephropathy JO: Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=25766759 #FOAvip About 70% of patients with primary membranous nephropathy (MN) have circulating anti-phospholipase A2 receptor (PLA2R) antibodies that correlate with disease activity, but their predictive value in post-transplant (Tx) recurrent MN is uncertain. We evaluated 26 patients, 18 with recurrent MN and 8 without recurrence, with serial post-Tx serum samples and renal biopsies to determine if patients with pre-Tx anti-PLA2R are at increased risk of recurrence as compared to seronegative patients and to determine if post-Tx changes in anti-PLA2R correspond to the clinical course. In the recurrent group, 10/17 patients had anti-PLA2R at the time of Tx vs. 2/7 patients in the non-recurrent group. The positive predictive value of pre-Tx anti-PLA2R for recurrence was 83%, while the negative predictive value was 42%. Persistence or reappearance of post-Tx anti-PLA2R was associated with increasing proteinuria and resistant disease in many cases; little or no proteinuria occurred in cases with pre-Tx anti-PLA2R and biopsy evidence of recurrence in which the antibodies resolved with standard immunosuppression. Some cases with positive pre-Tx anti-PLA2R were seronegative at the time of recurrence. In conclusion, patients with positive pre-Tx anti-PLA2R should be monitored closely for recurrent MN. Persistence or reappearance of antibody post-Tx may indicate a more resistant disease. Twit Text FOAVip Anti-Phospholipase A2 Receptor Antibodies in Recurrent Membranous Nephropathy ????Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=25766759 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25766759 #FOAvip English Wikipedia <ref>{{Cite pmid|25766759}}</ref> Anti-Phospholipase A2 Receptor Antibodies in Recurrent Membranous Nephropathy #MMPMID25766759 Kattah A; Ayalon R; Beck LH; Sandor DG; Cosio FG; Gandhi MJ; Sethi S; Lorenz EC; Salant DJ; Fervenza FC Am J Transplant 2015[May]; 15 (5): 1349-59 PMID25766759show ga About 70% of patients with primary membranous nephropathy (MN) have circulating anti-phospholipase A2 receptor (PLA2R) antibodies that correlate with disease activity, but their predictive value in post-transplant (Tx) recurrent MN is uncertain. We evaluated 26 patients, 18 with recurrent MN and 8 without recurrence, with serial post-Tx serum samples and renal biopsies to determine if patients with pre-Tx anti-PLA2R are at increased risk of recurrence as compared to seronegative patients and to determine if post-Tx changes in anti-PLA2R correspond to the clinical course. In the recurrent group, 10/17 patients had anti-PLA2R at the time of Tx vs. 2/7 patients in the non-recurrent group. The positive predictive value of pre-Tx anti-PLA2R for recurrence was 83%, while the negative predictive value was 42%. Persistence or reappearance of post-Tx anti-PLA2R was associated with increasing proteinuria and resistant disease in many cases; little or no proteinuria occurred in cases with pre-Tx anti-PLA2R and biopsy evidence of recurrence in which the antibodies resolved with standard immunosuppression. Some cases with positive pre-Tx anti-PLA2R were seronegative at the time of recurrence. In conclusion, patients with positive pre-Tx anti-PLA2R should be monitored closely for recurrent MN. Persistence or reappearance of antibody post-Tx may indicate a more resistant disease. äAnti-Phospholipase A2 Receptor Antibodies in Recurrent Membranous Neph(epmc).pdf DeepDyve Pubget Overpricing