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10.1016/j.stemcr.2015.05.002 http://scihub22266oqcxt.onion/10.1016/j.stemcr.2015.05.002 C4472038!4472038!26028532     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Stem+Cell+Reports 2015 ; 4 (6): 1112-24 Nephropedia Template TP {{tp|p=26028532|t=2015. KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas |pdf=|usr=}}{{26028532}} gab.com Text KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas JO: Stem Cell Reports http://www.kidney.de/pget.php?&tw=1&pmid=26028532 #FOAvip Differentiated derivatives of human pluripotent stem cells in culture are generally phenotypically immature compared to their adult counterparts. Their identity is often difficult to determine with certainty because little is known about their human fetal equivalents in vivo. Cellular identity and signaling pathways directing differentiation are usually determined by extrapolating information from either human adult tissue or model organisms, assuming conservation with humans. To resolve this, we generated a collection of human fetal transcriptional profiles at different developmental stages. Moreover, we developed an algorithm, KeyGenes, which uses this dataset to quantify the extent to which next-generation sequencing or microarray data resemble specific cell or tissue types in the human fetus. Using KeyGenes combined with the human fetal atlas, we identified multiple cell and tissue samples unambiguously on a limited set of features. We thus provide a flexible and expandable platform to monitor and evaluate the efficiency of differentiation in vitro. Twit Text FOAVip KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas ????Stem Cell Reports http://www.kidney.de/pget.php?&tw=1&pmid=26028532 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26028532 #FOAvip English Wikipedia <ref>{{Cite pmid|26028532}}</ref> KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas #MMPMID26028532 Roost M; van Iperen L; Ariyurek Y; Buermans H; Arindrarto W; Devalla H; Passier R; Mummery C; Carlotti F; de Koning E; van Zwet E; Goeman J; Chuva de Sousa Lopes S Stem Cell Reports 2015[Jun]; 4 (6): 1112-24 PMID26028532show ga Differentiated derivatives of human pluripotent stem cells in culture are generally phenotypically immature compared to their adult counterparts. Their identity is often difficult to determine with certainty because little is known about their human fetal equivalents in vivo. Cellular identity and signaling pathways directing differentiation are usually determined by extrapolating information from either human adult tissue or model organisms, assuming conservation with humans. To resolve this, we generated a collection of human fetal transcriptional profiles at different developmental stages. Moreover, we developed an algorithm, KeyGenes, which uses this dataset to quantify the extent to which next-generation sequencing or microarray data resemble specific cell or tissue types in the human fetus. Using KeyGenes combined with the human fetal atlas, we identified multiple cell and tissue samples unambiguously on a limited set of features. We thus provide a flexible and expandable platform to monitor and evaluate the efficiency of differentiation in vitro. äKeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal T(epmc).pdf DeepDyve Pubget Overpricing