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10.1590/1414-431X20153646 http://scihub22266oqcxt.onion/10.1590/1414-431X20153646 C4470309!4470309!25831205     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Braz+J+Med+Biol+Res 2015 ; 48 (6): 509-14 Nephropedia Template TP {{tp|p=25831205|t=2015. Circulating endothelial cells are increased in chronic myeloid leukemia blast crisis |pdf=|usr=}}{{25831205}} gab.com Text Circulating endothelial cells are increased in chronic myeloid leukemia blast crisis JO: Braz J Med Biol Res http://www.kidney.de/pget.php?&tw=1&pmid=25831205 #FOAvip We measured circulating endothelial precursor cells (EPCs), activated circulating endothelial cells (aCECs), and mature circulating endothelial cells (mCECs) using four-color multiparametric flow cytometry in the peripheral blood of 84 chronic myeloid leukemia (CML) patients and 65 healthy controls; and vascular endothelial growth factor (VEGF) by quantitative real-time PCR in 50 CML patients and 32 healthy controls. Because of an increase in mCECs, the median percentage of CECs in CML blast crisis (0.0146%) was significantly higher than in healthy subjects (0.0059%, P<0.01) and in the accelerated phase (0.0059%, P=0.01). There were no significant differences in the percentages of CECs in chronic- or active-phase patients and healthy subjects (P>0.05). In addition, VEGF gene expression was significantly higher in all phases of CML: 0.245 in blast crisis, 0.320 in the active phase, and 0.330 in chronic phase patients than it was in healthy subjects (0.145). In conclusion, CML in blast crisis had increased levels of CECs and VEGF gene expression, which may serve as markers of disease progression and may become targets for the management of CML. Twit Text FOAVip Circulating endothelial cells are increased in chronic myeloid leukemia blast crisis ????Braz J Med Biol Res http://www.kidney.de/pget.php?&tw=1&pmid=25831205 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25831205 #FOAvip English Wikipedia <ref>{{Cite pmid|25831205}}</ref> Circulating endothelial cells are increased in chronic myeloid leukemia blast crisis #MMPMID25831205 Godoy C; Levy D; Giampaoli V; Chamone D; Bydlowski S; Pereira J Braz J Med Biol Res 2015[Jun]; 48 (6): 509-14 PMID25831205show ga We measured circulating endothelial precursor cells (EPCs), activated circulating endothelial cells (aCECs), and mature circulating endothelial cells (mCECs) using four-color multiparametric flow cytometry in the peripheral blood of 84 chronic myeloid leukemia (CML) patients and 65 healthy controls; and vascular endothelial growth factor (VEGF) by quantitative real-time PCR in 50 CML patients and 32 healthy controls. Because of an increase in mCECs, the median percentage of CECs in CML blast crisis (0.0146%) was significantly higher than in healthy subjects (0.0059%, P<0.01) and in the accelerated phase (0.0059%, P=0.01). There were no significant differences in the percentages of CECs in chronic- or active-phase patients and healthy subjects (P>0.05). In addition, VEGF gene expression was significantly higher in all phases of CML: 0.245 in blast crisis, 0.320 in the active phase, and 0.330 in chronic phase patients than it was in healthy subjects (0.145). In conclusion, CML in blast crisis had increased levels of CECs and VEGF gene expression, which may serve as markers of disease progression and may become targets for the management of CML. äCirculating endothelial cells are increased in chronic myeloid leukemi(epmc).pdf DeepDyve Pubget Overpricing