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10.3390/jcm4050858

http://scihub22266oqcxt.onion/10.3390/jcm4050858
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C4470203!4470203!26239452
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suck abstract from ncbi


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pmid26239452      J+Clin+Med 2015 ; 4 (5): 858-73
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  • Immune Pathways in Atopic Dermatitis, and Definition of Biomarkers through Broad and Targeted Therapeutics #MMPMID26239452
  • Mansouri Y; Guttman-Yassky E
  • J Clin Med 2015[May]; 4 (5): 858-73 PMID26239452show ga
  • Atopic dermatitis (AD) is the most common inflammatory skin disease. Recent research findings have provided an insight into the complex pathogenic mechanisms involved in this disease. Despite a rising prevalence, effective and safe therapeutics for patients with moderate-to-severe AD are still lacking. Biomarkers of lesional, nonlesional skin, and blood have been developed for baseline as well as after treatment with broad and specific treatments (i.e., cyclosporine A and dupilumab). These biomarkers will help with the development of novel targeted therapeutics and assessment of disease reversal, with the promise of a more personalized treatment approach. Since AD involves more than one subtype (i.e., intrinsic/extrinsic, pediatric/adult, etc.), these molecular fingerprints needs to be validated in all subpopulations with AD.
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