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10.3390/jcm4030441

http://scihub22266oqcxt.onion/10.3390/jcm4030441
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C4470138!4470138!26239248
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suck abstract from ncbi


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pmid26239248      J+Clin+Med 2015 ; 4 (3): 441-59
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  • Treatment of Acute Myeloid Leukemia in Adolescent and Young Adult Patients #MMPMID26239248
  • Cengiz Seval G; Ozcan M
  • J Clin Med 2015[Mar]; 4 (3): 441-59 PMID26239248show ga
  • The objectives of this review were to discuss standard and investigational treatment strategies for adolescent and young adult with acute myeloid leukemia, excluding acute promyelocytic leukemia. Acute myeloid leukemia (AML) in adolescent and young adult patients (AYAs) may need a different type of therapy than those currently used in children and older patients. As soon as AML is diagnosed, AYA patient should be offered to participate in well-designed clinical trials. The standard treatment approach for AYAs with AML is remission induction chemotherapy with an anthracycline/cytarabine combination, followed by either consolidation chemotherapy or stem cell transplantation, depending on the ability of the patient to tolerate intensive treatment and cytogenetic features. Presently, continuing progress of novel drugs targeting specific pathways in acute leukemia may bring AML treatment into a new era.
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