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10.17305/bjbms.2015.449 http://scihub22266oqcxt.onion/10.17305/bjbms.2015.449 C4469930!4469930!26042506     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Bosn+J+Basic+Med+Sci 2015 ; 15 (2): 1-8 Nephropedia Template TP {{tp|p=26042506|t=2015. Prostate cancer stroma: an important factor in cancer growth and progression |pdf=|usr=}}{{26042506}} gab.com Text Prostate cancer stroma: an important factor in cancer growth and progression JO: Bosn J Basic Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=26042506 #FOAvip Reactive stromal changes that occur in different human cancers might play a role in local tumor spreading and progression. Studies done on various human cancers have shown activated stromal cell phenotypes, modified extracellular matrix (ECM) composition, and increased microvessel density. Furthermore, they exhibit biological markers consistent with stroma at the site of wound repair. In prostate cancer, stroma is composed of fibroblasts, myofibroblasts, endothelial cells and immune cells. Predominant cells in the tumorous stroma are, however, fibroblasts/myofibroblasts. They are responsible for the synthesis, deposition and remodeling of the ECM. Epithelial tumorous cells, in interaction with stromal cells and with the help of various molecules of ECM, create a microenvironment suitable for cancer cell proliferation, movement, and differentiation. In this review, we discussed the role of different stromal components in prostate cancer as well as their potential prognostic and therapeutic significance. Twit Text FOAVip Prostate cancer stroma: an important factor in cancer growth and progression ????Bosn J Basic Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=26042506 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26042506 #FOAvip English Wikipedia <ref>{{Cite pmid|26042506}}</ref> Prostate cancer stroma: an important factor in cancer growth and progression #MMPMID26042506 Kru?lin B; Ulamec M; Tomas D Bosn J Basic Med Sci 2015[May]; 15 (2): 1-8 PMID26042506show ga Reactive stromal changes that occur in different human cancers might play a role in local tumor spreading and progression. Studies done on various human cancers have shown activated stromal cell phenotypes, modified extracellular matrix (ECM) composition, and increased microvessel density. Furthermore, they exhibit biological markers consistent with stroma at the site of wound repair. In prostate cancer, stroma is composed of fibroblasts, myofibroblasts, endothelial cells and immune cells. Predominant cells in the tumorous stroma are, however, fibroblasts/myofibroblasts. They are responsible for the synthesis, deposition and remodeling of the ECM. Epithelial tumorous cells, in interaction with stromal cells and with the help of various molecules of ECM, create a microenvironment suitable for cancer cell proliferation, movement, and differentiation. In this review, we discussed the role of different stromal components in prostate cancer as well as their potential prognostic and therapeutic significance. äProstate cancer stroma: an important factor in cancer growth and progr(epmc).pdf DeepDyve Pubget Overpricing