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10.3389/fmed.2015.00033 http://scihub22266oqcxt.onion/10.3389/fmed.2015.00033 C4469113!4469113!26131447     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Med+(Lausanne) 2015 ; 2 (ä): ä Nephropedia Template TP {{tp|p=26131447|t=2015. NK Cell Inflammation in the Clinical Outcome of Colorectal Carcinoma |pdf=|usr=}}{{26131447}} gab.com Text NK Cell Inflammation in the Clinical Outcome of Colorectal Carcinoma JO: Front Med (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=26131447 #FOAvip The ability of natural killer (NK) cells to provide protection against myeloid leukemia has been demonstrated in clinical settings. However, whether NK cells play a role in the clinical course of solid tumors is debated. The controversy surrounding the role of NK cells is due, at least in part, to the limited extent of NK cell infiltration found in the tumor bed. Inactivation of NK cells may explain the shortage of NK cells in the microenvironment of colorectal cancer (CRC). Upon NK cell/tumor cell interaction, tumor cells may escape NK cells by creating an immunosuppressive microenvironment, which possibly affects T-cells as well. Such an immunosuppressive microenvironment would hamper the functions of NK and T-cell and reduce NK and T-cell interactions. CRC patients with levels of tumor NK cell infiltration suitable for statistical analysis have been identified. The infiltration of the CRC microenvironment by NK cells, in combination with CD8+ T-lymphocytes, has been shown to enhance the prognosis of CRC patients. Here, we discuss the clinicopathological role of NK cells in CRC, and present clinical data indicating a potential supporting role for NK cells in the anti-CRC effects of CD8+ T-cells. Twit Text FOAVip NK Cell Inflammation in the Clinical Outcome of Colorectal Carcinoma ????Front Med (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=26131447 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26131447 #FOAvip English Wikipedia <ref>{{Cite pmid|26131447}}</ref> NK Cell Inflammation in the Clinical Outcome of Colorectal Carcinoma #MMPMID26131447 Coppola A; Arriga R; Lauro D; del Principe MI; Buccisano F; Maurillo L; Palomba P; Venditti A; Sconocchia G Front Med (Lausanne) 2015[]; 2 (ä): ä PMID26131447show ga The ability of natural killer (NK) cells to provide protection against myeloid leukemia has been demonstrated in clinical settings. However, whether NK cells play a role in the clinical course of solid tumors is debated. The controversy surrounding the role of NK cells is due, at least in part, to the limited extent of NK cell infiltration found in the tumor bed. Inactivation of NK cells may explain the shortage of NK cells in the microenvironment of colorectal cancer (CRC). Upon NK cell/tumor cell interaction, tumor cells may escape NK cells by creating an immunosuppressive microenvironment, which possibly affects T-cells as well. Such an immunosuppressive microenvironment would hamper the functions of NK and T-cell and reduce NK and T-cell interactions. CRC patients with levels of tumor NK cell infiltration suitable for statistical analysis have been identified. The infiltration of the CRC microenvironment by NK cells, in combination with CD8+ T-lymphocytes, has been shown to enhance the prognosis of CRC patients. Here, we discuss the clinicopathological role of NK cells in CRC, and present clinical data indicating a potential supporting role for NK cells in the anti-CRC effects of CD8+ T-cells. äNK Cell Inflammation in the Clinical Outcome of Colorectal Carcinoma (epmc).pdf DeepDyve Pubget Overpricing