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10.1155/2015/549432 http://scihub22266oqcxt.onion/10.1155/2015/549432 C4468342!4468342!26136785     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Stem+Cells+Int 2015 ; 2015 (ä): ä Nephropedia Template TP {{tp|p=26136785|t=2015. Human Umbilical Cord Mesenchymal Stem Cells: A New Therapeutic Option for Tooth Regeneration |pdf=|usr=}}{{26136785}} gab.com Text Human Umbilical Cord Mesenchymal Stem Cells: A New Therapeutic Option for Tooth Regeneration JO: Stem Cells Int http://www.kidney.de/pget.php?&tw=1&pmid=26136785 #FOAvip Tooth regeneration is considered to be an optimistic approach to replace current treatments for tooth loss. It is important to determine the most suitable seed cells for tooth regeneration. Recently, human umbilical cord mesenchymal stem cells (hUCMSCs) have been regarded as a promising candidate for tissue regeneration. However, it has not been reported whether hUCMSCs can be employed in tooth regeneration. Here, we report that hUCMSCs can be induced into odontoblast-like cells in vitro and in vivo. Induced hUCMSCs expressed dentin-related proteins including dentin sialoprotein (DSP) and dentin matrix protein-1 (DMP-1), and their gene expression levels were similar to those in native pulp tissue cells. Moreover, DSP- and DMP-1-positive calcifications were observed after implantation of hUCMSCs in vivo. These findings reveal that hUCMSCs have an odontogenic differentiation potency to differentiate to odontoblast-like cells with characteristic deposition of dentin-like matrix in vivo. This study clearly demonstrates hUCMSCs as an alternative therapeutic cell source for tooth regeneration. Twit Text FOAVip Human Umbilical Cord Mesenchymal Stem Cells: A New Therapeutic Option for Tooth Regeneration ????Stem Cells Int http://www.kidney.de/pget.php?&tw=1&pmid=26136785 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26136785 #FOAvip English Wikipedia <ref>{{Cite pmid|26136785}}</ref> Human Umbilical Cord Mesenchymal Stem Cells: A New Therapeutic Option for Tooth Regeneration #MMPMID26136785 Chen Y; Yu Y; Chen L; Ye L; Cui J; Sun Q; Li K; Li Z; Liu L Stem Cells Int 2015[]; 2015 (ä): ä PMID26136785show ga Tooth regeneration is considered to be an optimistic approach to replace current treatments for tooth loss. It is important to determine the most suitable seed cells for tooth regeneration. Recently, human umbilical cord mesenchymal stem cells (hUCMSCs) have been regarded as a promising candidate for tissue regeneration. However, it has not been reported whether hUCMSCs can be employed in tooth regeneration. Here, we report that hUCMSCs can be induced into odontoblast-like cells in vitro and in vivo. Induced hUCMSCs expressed dentin-related proteins including dentin sialoprotein (DSP) and dentin matrix protein-1 (DMP-1), and their gene expression levels were similar to those in native pulp tissue cells. Moreover, DSP- and DMP-1-positive calcifications were observed after implantation of hUCMSCs in vivo. These findings reveal that hUCMSCs have an odontogenic differentiation potency to differentiate to odontoblast-like cells with characteristic deposition of dentin-like matrix in vivo. This study clearly demonstrates hUCMSCs as an alternative therapeutic cell source for tooth regeneration. äHuman Umbilical Cord Mesenchymal Stem Cells: A New Therapeutic Option (epmc).pdf DeepDyve Pubget Overpricing