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http://scihub22266oqcxt.onion/ C4466938!4466938!26097551     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Clin+Exp+Pathol 2015 ; 8 (4): 3701-9 Nephropedia Template TP {{tp|p=26097551|t=2015. Krüppel-like factors 4 and 5 expression and their involvement in differentiation of oral carcinomas |pdf=|usr=}}{{26097551}} gab.com Text Krüppel-like factors 4 and 5 expression and their involvement in differentiation of oral carcinomas JO: Int J Clin Exp Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26097551 #FOAvip Proliferation-differentiation balance of epithelial cells is regulated by krüppel-like factors (KLF) 4 and 5, and the unbalanced expression relates to carcinoma progression. However, little is known about the expression and role in oral carcinomas. This study examined expression of KLF4 and KLF 5 in the carcinomas by immunohistochemistry (n = 67) and the involvement in proliferation and differentiation of carcinoma cells. KLF4 was detected in keratinizing carcinoma cells and KLF5 in non-keratinizing cells. KLF4 staining declined in the patient with lymph node metastasis (P < 0.05) and in parallel with the histological dedifferentiation (P = 0.09). Exogenous overexpression of KLF4 arranged cells in a cobble-like structure with desmosomes and KLF5 elongated cells like fibroblasts without desmosomes. KLF4 suppressed fibronectin expression, and KLF5 down-regulated and degraded E-cadherin. The proliferation was not affected by KLFs. Thus, down-regulation of KLF4 and up-regulation of KLF5 may stimulate oral carcinoma progression through the dedifferentiation of carcinoma cells. Twit Text FOAVip Krüppel-like factors 4 and 5 expression and their involvement in differentiation of oral carcinomas ????Int J Clin Exp Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26097551 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26097551 #FOAvip English Wikipedia <ref>{{Cite pmid|26097551}}</ref> Krüppel-like factors 4 and 5 expression and their involvement in differentiation of oral carcinomas #MMPMID26097551 Shibata M; Chiba T; Matsuoka T; Mihara N; Kawashiri S; Imai K Int J Clin Exp Pathol 2015[]; 8 (4): 3701-9 PMID26097551show ga Proliferation-differentiation balance of epithelial cells is regulated by krüppel-like factors (KLF) 4 and 5, and the unbalanced expression relates to carcinoma progression. However, little is known about the expression and role in oral carcinomas. This study examined expression of KLF4 and KLF 5 in the carcinomas by immunohistochemistry (n = 67) and the involvement in proliferation and differentiation of carcinoma cells. KLF4 was detected in keratinizing carcinoma cells and KLF5 in non-keratinizing cells. KLF4 staining declined in the patient with lymph node metastasis (P < 0.05) and in parallel with the histological dedifferentiation (P = 0.09). Exogenous overexpression of KLF4 arranged cells in a cobble-like structure with desmosomes and KLF5 elongated cells like fibroblasts without desmosomes. KLF4 suppressed fibronectin expression, and KLF5 down-regulated and degraded E-cadherin. The proliferation was not affected by KLFs. Thus, down-regulation of KLF4 and up-regulation of KLF5 may stimulate oral carcinoma progression through the dedifferentiation of carcinoma cells. äKrüppel-like factors 4 and 5 expression and their involvement in diffe(epmc).pdf DeepDyve Pubget Overpricing