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10.1073/pnas.1507977112 http://scihub22266oqcxt.onion/10.1073/pnas.1507977112 C4466754!4466754!26015573     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2015 ; 112 (23): 7219-24 Nephropedia Template TP {{tp|p=26015573|t=2015. Human HLA-G+ extravillous trophoblasts: Immune-activating cells that interact with decidual leukocytes |pdf=|usr=}}{{26015573}} gab.com Text Human HLA-G+ extravillous trophoblasts: Immune-activating cells that interact with decidual leukocytes JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26015573 #FOAvip Fetal extravillous trophoblasts (EVT) invade uterine tissue and interact with maternal immune cells during pregnancy. EVT express human leukocyte antigen-C (HLA-C) and -G (HLA-G). Although polymorphic HLA-C can elicit a maternal immune response, HLA-G has been associated with induction of immune tolerance. We have succeeded in isolating all maternal immune cell types as well as EVT from human placental tissue. These methods were used to elucidate the unique charateristics of EVT as well as their interaction with maternal immune cells. We demonstrate that EVT are specialized cells whose properties are not imitated by HLA?G?expressing surrogate cell lines. Studies using primary EVT are crucial for understanding maternal?fetal tolerance and development of pregnancy complications such as preeclampsia and miscarriages. Twit Text FOAVip Human HLA-G+ extravillous trophoblasts: Immune-activating cells that interact with decidual leukocytes ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26015573 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26015573 #FOAvip English Wikipedia <ref>{{Cite pmid|26015573}}</ref> Human HLA-G+ extravillous trophoblasts: Immune-activating cells that interact with decidual leukocytes #MMPMID26015573 Tilburgs T; Crespo ĀC; van der Zwan A; Rybalov B; Raj T; Stranger B; Gardner L; Moffett A; Strominger JL Proc Natl Acad Sci U S A 2015[Jun]; 112 (23): 7219-24 PMID26015573show ga Fetal extravillous trophoblasts (EVT) invade uterine tissue and interact with maternal immune cells during pregnancy. EVT express human leukocyte antigen-C (HLA-C) and -G (HLA-G). Although polymorphic HLA-C can elicit a maternal immune response, HLA-G has been associated with induction of immune tolerance. We have succeeded in isolating all maternal immune cell types as well as EVT from human placental tissue. These methods were used to elucidate the unique charateristics of EVT as well as their interaction with maternal immune cells. We demonstrate that EVT are specialized cells whose properties are not imitated by HLA?G?expressing surrogate cell lines. Studies using primary EVT are crucial for understanding maternal?fetal tolerance and development of pregnancy complications such as preeclampsia and miscarriages. äHuman HLA-G+ extravillous trophoblasts: Immune-activating cells that i(epmc).pdf DeepDyve Pubget Overpricing