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2015 ; 44
(6
): 666-71
Nephropedia Template TP
gab.com Text
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English Wikipedia
Reasons for failure to receive pneumococcal and influenza vaccinations among
immunosuppressed patients with systemic lupus erythematosus
#MMPMID25701500
Lawson EF
; Trupin L
; Yelin EH
; Yazdany J
Semin Arthritis Rheum
2015[Jun]; 44
(6
): 666-71
PMID25701500
show ga
OBJECTIVE: To better understand why immunosuppressed individuals with systemic
lupus erythematosus (SLE) fail to receive influenza and pneumococcal vaccines.
METHODS: These cross-sectional data were derived from the 2009 cycle of the Lupus
Outcomes Study (LOS), an annual longitudinal telephone survey of individuals with
confirmed SLE. Respondents were included in the analysis if they had taken
immunosuppressive medications in the past year. We assessed any prior receipt of
pneumococcal vaccine and influenza vaccine in the past year, and then elicited
reasons for not receiving vaccination. We used bivariate statistics and
multivariate logistic regression to assess frequency and predictors of reported
reasons for not obtaining influenza or pneumococcal vaccines. RESULTS: Among 508
respondents who received immunosuppressants, 485 reported whether they had
received vaccines. Among the 175 respondents who did not receive an influenza
vaccine, the most common reason was lack of doctor recommendation (55%), followed
by efficacy or safety concerns (21%), and lack of time (19%). Reasons for not
receiving pneumococcal vaccine (N = 159) were similar: lack of recommendation
(87%), lack of time (7%), and efficacy or safety concerns (4%). Younger,
less-educated, non-white patients with shorter disease duration, as well as those
immunosuppressed with steroids alone, were at the greatest risk for not receiving
indicated vaccine recommendations. CONCLUSIONS: The most common reason why
individuals with SLE did not receive pneumococcal and influenza vaccines was that
physicians failed to recommend them. Data suggest that increasing vaccination
rates in SLE will require improved process quality at the provider level, as well
as addressing patient concerns and barriers.
|*Immunocompromised Host
[MESH]
|Adult
[MESH]
|Age Factors
[MESH]
|Cross-Sectional Studies
[MESH]
|Female
[MESH]
|Guideline Adherence
[MESH]
|Humans
[MESH]
|Immunosuppressive Agents/*adverse effects
[MESH]
|Influenza Vaccines/*therapeutic use
[MESH]
|Influenza, Human/etiology/*prevention & control
[MESH]