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suck abstract from ncbi


10.1016/j.earlhumdev.2013.09.012

http://scihub22266oqcxt.onion/10.1016/j.earlhumdev.2013.09.012
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C4464839!4464839!24083892
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suck abstract from ncbi


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pmid24083892      Early+Hum+Dev 2013 ; 89 (11): 865-74
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  • Diagnosis and treatment of pulmonary hypertension in infancy #MMPMID24083892
  • Steinhorn RH
  • Early Hum Dev 2013[Nov]; 89 (11): 865-74 PMID24083892show ga
  • Normal pulmonary vascular development in infancy requires maintenance of low pulmonary vascular resistance after birth, and is necessary for normal lung function and growth. The developing lung is subject to multiple genetic, pathological and/or environmental influences that can adversely affect lung adaptation, development, and growth, leading to pulmonary hypertension. New classifications of pulmonary hypertension are beginning to account for these diverse phenotypes, and or pulmonary hypertension in infants due to PPHN, congenital diaphragmatic hernia, and bronchopulmonary dysplasia (BPD). The most effective pharmacotherapeutic strategies for infants with PPHN are directed at selective reduction of PVR, and take advantage of a rapidly advancing understanding of the altered signaling pathways in the remodeled vasculature.
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