Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.tig.2009.05.005 http://scihub22266oqcxt.onion/10.1016/j.tig.2009.05.005 C4464790!4464790!19560228     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Genet 2009 ; 25 (7): 298-307 Nephropedia Template TP {{tp|p=19560228|t=2009. Complex human chromosomal and genomic rearrangements |pdf=|usr=}}{{19560228}} gab.com Text Complex human chromosomal and genomic rearrangements JO: Trends Genet http://www.kidney.de/pget.php?&tw=1&pmid=19560228 #FOAvip Copy number variation (CNV) is a major source of genetic variation among humans. In addition to existing as benign polymorphisms, CNVs can also convey clinical phenotypes, including genomic disorders, sporadic diseases and complex human traits. CNV results from genomic rearrangements that can represent simple deletion or duplication of a genomic segment, or be more complex. Complex chromosomal rearrangements (CCRs) have been known for some time but their mechanisms have remained elusive. Recent technology advances and high-resolution human genome analyses have revealed that complex genomic rearrangements can account for a large fraction of non-recurrent rearrangements at a given locus. Various mechanisms, most of which are DNA-replication-based, for example fork stalling and template switching (FoSTeS) and microhomology-mediated break-induced replication (MMBIR), have been proposed for generating such complex genomic rearrangements and are probably responsible for CCR. Twit Text FOAVip Complex human chromosomal and genomic rearrangements ????Trends Genet http://www.kidney.de/pget.php?&tw=1&pmid=19560228 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=19560228 #FOAvip English Wikipedia <ref>{{Cite pmid|19560228}}</ref> Complex human chromosomal and genomic rearrangements #MMPMID19560228 Zhang F; Carvalho CM; Lupski JR Trends Genet 2009[Jul]; 25 (7): 298-307 PMID19560228show ga Copy number variation (CNV) is a major source of genetic variation among humans. In addition to existing as benign polymorphisms, CNVs can also convey clinical phenotypes, including genomic disorders, sporadic diseases and complex human traits. CNV results from genomic rearrangements that can represent simple deletion or duplication of a genomic segment, or be more complex. Complex chromosomal rearrangements (CCRs) have been known for some time but their mechanisms have remained elusive. Recent technology advances and high-resolution human genome analyses have revealed that complex genomic rearrangements can account for a large fraction of non-recurrent rearrangements at a given locus. Various mechanisms, most of which are DNA-replication-based, for example fork stalling and template switching (FoSTeS) and microhomology-mediated break-induced replication (MMBIR), have been proposed for generating such complex genomic rearrangements and are probably responsible for CCR. äComplex human chromosomal and genomic rearrangements (epmc).pdf DeepDyve Pubget Overpricing