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10.1186/s12902-015-0024-3 http://scihub22266oqcxt.onion/10.1186/s12902-015-0024-3 C4464624!4464624!26063496     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMC+Endocr+Disord 2015 ; 15 (ä): ä Nephropedia Template TP {{tp|p=26063496|t=2015. Paediatric cyclical Cushing?s disease due to corticotroph cell hyperplasia |pdf=|usr=}}{{26063496}} gab.com Text Paediatric cyclical Cushing s disease due to corticotroph cell hyperplasia JO: BMC Endocr Disord http://www.kidney.de/pget.php?&tw=1&pmid=26063496 #FOAvip Background: Cushing?s disease is very rare in the paediatric population. Although uncommon, corticotroph hyperplasia causing Cushing?s syndrome has been described in the adult population, but appears to be extremely rare in children. Likewise, cyclical cortisol hypersecretion, while accounting for 15 % of adult cases of Cushing?s disease, has only rarely been described in the paediatric population. Here, we describe a very rare case of a 13-year old boy with cyclical cortisol hypersecretion secondary to corticotroph cell hyperplasia. Case presentation: The case is that of a 13-year old boy, presenting with a long history of symptoms and signs suggestive of hypercortisolism, who was found to have cyclical ACTH-dependent hypercortisolism following dynamic pituitary testing and serial late-night salivary cortisol measurements. The patient underwent endoscopic transsphenoidal resection of the pituitary. Early surgical remission was confirmed by undetectable post-operative morning plasma cortisol levels. Histology and immunocytochemistry of the resected pituitary tissue showed extensive corticotroph cell hyperplasia. Conclusion: This report describes a rare case of cyclical Cushing?s disease secondary to corticotroph hyperplasia in a paediatric patient. This highlights the challenging and varied nature of Cushing?s disease and its diagnosis, and the need to keep a differential diagnosis in mind during the diagnostic process. Twit Text FOAVip Paediatric cyclical Cushing s disease due to corticotroph cell hyperplasia ????BMC Endocr Disord http://www.kidney.de/pget.php?&tw=1&pmid=26063496 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26063496 #FOAvip English Wikipedia <ref>{{Cite pmid|26063496}}</ref> Paediatric cyclical Cushing?s disease due to corticotroph cell hyperplasia #MMPMID26063496 Noctor E; Gupta S; Brown T; Farrell M; Javadpour M; Costigan C; Agha A BMC Endocr Disord 2015[]; 15 (ä): ä PMID26063496show ga Background: Cushing?s disease is very rare in the paediatric population. Although uncommon, corticotroph hyperplasia causing Cushing?s syndrome has been described in the adult population, but appears to be extremely rare in children. Likewise, cyclical cortisol hypersecretion, while accounting for 15 % of adult cases of Cushing?s disease, has only rarely been described in the paediatric population. Here, we describe a very rare case of a 13-year old boy with cyclical cortisol hypersecretion secondary to corticotroph cell hyperplasia. Case presentation: The case is that of a 13-year old boy, presenting with a long history of symptoms and signs suggestive of hypercortisolism, who was found to have cyclical ACTH-dependent hypercortisolism following dynamic pituitary testing and serial late-night salivary cortisol measurements. The patient underwent endoscopic transsphenoidal resection of the pituitary. Early surgical remission was confirmed by undetectable post-operative morning plasma cortisol levels. Histology and immunocytochemistry of the resected pituitary tissue showed extensive corticotroph cell hyperplasia. Conclusion: This report describes a rare case of cyclical Cushing?s disease secondary to corticotroph hyperplasia in a paediatric patient. This highlights the challenging and varied nature of Cushing?s disease and its diagnosis, and the need to keep a differential diagnosis in mind during the diagnostic process. äPaediatric cyclical Cushing?s disease due to corticotroph cell hyperpl(epmc).pdf DeepDyve Pubget Overpricing