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2014 ; 13
(ä): 801-8
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An overview of platelet indices for evaluating platelet function in children with
scorpion envenomation
#MMPMID26417303
Konca C
; Tekin M
; Colak P
; Uckardes F
; Turgut M
EXCLI J
2014[]; 13
(ä): 801-8
PMID26417303
show ga
The aim of this study was to assess the correlation between platelet indices and
scorpion envenomations (SE). Medical records of 76 children who were hospitalised
for scorpion stings in the paediatric intensive care unit (PICU) between February
2013 and November 2013, and 55 healthy children who were similar to the patient
group in terms of age and sex, were analysed retrospectively. The leucocyte
(WBC), thrombocyte (PLT), plateletcrit (PCT), platelet distribution width (PDW)
and mean platelet volume (MPV) values of the 76 children with SE were recorded.
These values were compared with the healthy control group. Significantly higher
WBC and PDW values were noted in patients with SE in comparison to the controls.
Patients with SE had significantly lower mean MPV values compared to the healthy
controls (9.03 ± 1.26 compared to 10.43 ± 1.44 fL, respectively; p < 0.001).
Although the mean platelet count was slightly elevated in the SE group, no
statistically significant difference existed between the two groups (p = 0.097).
Furthermore, the mean PCT values in the SE group compared to the control group
were slightly decreased, but this decrease was not statistically significant (p =
0.141). A significant inverse correlation existed between the MPV values and the
WBC (r = -0.450, p < 0.01) and PLT counts (r = -0.420, p < 0.01). The PLT values
were significantly correlated with the PCT values (r = 0.687, p < 0.01). This
study demonstrated that SE may lead to several alterations in platelet indices.
Significantly lower values of MPV and higher values of PDW were detected in SE
patients. However, the increase in the platelet counts and the decrease in the
PCT values were not significant.
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