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10.1111/ijs.12054

http://scihub22266oqcxt.onion/10.1111/ijs.12054
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C4463944!4463944!23692610
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suck abstract from ncbi


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pmid23692610      Int+J+Stroke 2015 ; 10 (3): 376-81
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  • Enlarged perivascular spaces and cerebral small vessel disease #MMPMID23692610
  • Potter GM; Doubal FN; Jackson CA; Chappell FM; Sudlow CL; Dennis MS; Wardlaw JM
  • Int J Stroke 2015[Apr]; 10 (3): 376-81 PMID23692610show ga
  • Background and aims: Enlarged perivascular spaces (also known as Virchow?Robin spaces) on T2-weighted brain magnetic resonance imaging are common, but their etiology, and specificity to small vessel as opposed to general cerebrovascular disease or ageing, is unclear. We tested the association between enlarged perivascular spaces and ischemic stroke subtype, other markers of small vessel disease, and common vascular risk factors. Methods: We prospectively recruited patients with acute stroke, diagnosed and subtyped by a stroke physician using clinical features and brain magnetic resonance imaging. A neuroradiologist rated basal ganglia and centrum semiovale enlarged perivascular spaces on a five-point scale, white matter lesions, recent and old infarcts, and cerebral atrophy. We assessed associations between basal ganglia-, centrum semiovale- and total (combined basal ganglia and centrum semiovale) enlarged perivascular spaces, stroke subtype, white matter lesions, atrophy, and vascular risk factors. Results: Among 298 patients (mean age 68 years), after adjusting for vascular risk factors and white matter lesions, basal ganglia?enlarged perivascular spaces were associated with increasing age (P?=?0·001), centrum semiovale?enlarged perivascular spaces (P?
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