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10.3390/ijms160511055 http://scihub22266oqcxt.onion/10.3390/ijms160511055 C4463690!4463690!25988385     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2015 ; 16 (5): 11055-86 Nephropedia Template TP {{tp|p=25988385|t=2015. Molecular Connections between Cancer Cell Metabolism and the Tumor Microenvironment |pdf=|usr=}}{{25988385}} gab.com Text Molecular Connections between Cancer Cell Metabolism and the Tumor Microenvironment JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=25988385 #FOAvip Cancer cells preferentially utilize glycolysis, instead of oxidative phosphorylation, for metabolism even in the presence of oxygen. This phenomenon of aerobic glycolysis, referred to as the ?Warburg effect?, commonly exists in a variety of tumors. Recent studies further demonstrate that both genetic factors such as oncogenes and tumor suppressors and microenvironmental factors such as spatial hypoxia and acidosis can regulate the glycolytic metabolism of cancer cells. Reciprocally, altered cancer cell metabolism can modulate the tumor microenvironment which plays important roles in cancer cell somatic evolution, metastasis, and therapeutic response. In this article, we review the progression of current understandings on the molecular interaction between cancer cell metabolism and the tumor microenvironment. In addition, we discuss the implications of these interactions in cancer therapy and chemoprevention. Twit Text FOAVip Molecular Connections between Cancer Cell Metabolism and the Tumor Microenvironment ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=25988385 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25988385 #FOAvip English Wikipedia <ref>{{Cite pmid|25988385}}</ref> Molecular Connections between Cancer Cell Metabolism and the Tumor Microenvironment #MMPMID25988385 Justus CR; Sanderlin EJ; Yang LV Int J Mol Sci 2015[May]; 16 (5): 11055-86 PMID25988385show ga Cancer cells preferentially utilize glycolysis, instead of oxidative phosphorylation, for metabolism even in the presence of oxygen. This phenomenon of aerobic glycolysis, referred to as the ?Warburg effect?, commonly exists in a variety of tumors. Recent studies further demonstrate that both genetic factors such as oncogenes and tumor suppressors and microenvironmental factors such as spatial hypoxia and acidosis can regulate the glycolytic metabolism of cancer cells. Reciprocally, altered cancer cell metabolism can modulate the tumor microenvironment which plays important roles in cancer cell somatic evolution, metastasis, and therapeutic response. In this article, we review the progression of current understandings on the molecular interaction between cancer cell metabolism and the tumor microenvironment. In addition, we discuss the implications of these interactions in cancer therapy and chemoprevention. äMolecular Connections between Cancer Cell Metabolism and the Tumor Mic(epmc).pdf DeepDyve Pubget Overpricing