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2015 ; 21
(1
): 22-7
Nephropedia Template TP
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Vacuum-assisted stereotactic biopsy for isolated BI-RADS 4 microcalcifications:
evaluation with histopathology and midterm follow-up results
#MMPMID25323837
Atasoy MM
; Tasali N
; Çubuk R
; Narin B
; Deveci U
; Yener N
; Çelik L
Diagn Interv Radiol
2015[Jan]; 21
(1
): 22-7
PMID25323837
show ga
PURPOSE: The aim of this study was to evaluate the 10-gauge vacuum-assisted
stereotactic biopsy (VASB) of isolated Breast Imaging Reporting and Data System
(BI-RADS) 4 microcalcifications, using histology and follow-up results. METHODS:
From January 2011 to June 2013, VASB was performed on 132 lesions, and 66
microcalcification-only lesions of BI-RADS 4 were included into our study. VASB
was performed using lateral decubitis stereotaxy for all patients. Pathologic
results of VASB and further surgical biopsies were reviewed retrospectively.
Patients who were diagnosed to have benign lesions by VASB were referred for
follow-up. VASB and surgical histopathology results were compared to determine
the underestimation ratios. RESULTS: Fifteen out of 66 lesions from 63 patients
(median age, 47 years; range, 34-88 years) were identified as malignant by VASB.
Pathological results after surgery revealed three cases of invasive ductal
carcinoma among the 12 VASB-diagnosed ductal carcinoma in situ (DCIS) lesions,
for a DCIS underestimation rate of 25%. The atypical ductal hyperplasia
underestimation rate was 0% for the three lesions. The follow-up period was at
least 10 months, with an average of 22.7 months for all patients and 21.2 months
for patients with VASB-diagnosed benign lesions. None of the patients had
malignancy during the follow-ups. The false-negative rate was 0% in the follow-up
of 48 patients. CONCLUSION: VASB should be the standard method of choice for
BI-RADS 4 microcalcifications. This method obviates the need for a surgical
procedure in 73% of BI-RADS 4 microcalcification-only patients.