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10.1186/s13287-015-0108-z http://scihub22266oqcxt.onion/10.1186/s13287-015-0108-z C4462013!4462013!26062806     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Stem+Cell+Res+Ther 2015 ; 6 (1): ä Nephropedia Template TP {{tp|p=26062806|t=2015. Ex vivo manipulation of bone marrow cells to rescue uremia-induced dysfunction for autologous therapy |pdf=|usr=}}{{26062806}} gab.com Text Ex vivo manipulation of bone marrow cells to rescue uremia-induced dysfunction for autologous therapy JO: Stem Cell Res Ther http://www.kidney.de/pget.php?&tw=1&pmid=26062806 #FOAvip Uremic toxins are known to affect the regenerative properties of tissue-resident and circulating stem cells and thus appear to be a limiting factor for autologous stem cell-based approaches for treating chronic kidney disease. The recent article by van Koppen and colleagues in Stem Cell Research & Therapy provides evidence that an ex vivo short-term pre-treatment with statins reverts the dysfunction of bone marrow stem cells isolated from rats with renal impairment. Indeed, statin pre-treated cells improved renal function in a model of established chronic kidney disease. Our commentary discusses the potential of this approach in the context of autologous cell therapy and the available knowledge on the mechanisms involved in uremia-induced stem cell dysfunction. Twit Text FOAVip Ex vivo manipulation of bone marrow cells to rescue uremia-induced dysfunction for autologous therapy ????Stem Cell Res Ther http://www.kidney.de/pget.php?&tw=1&pmid=26062806 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26062806 #FOAvip English Wikipedia <ref>{{Cite pmid|26062806}}</ref> Ex vivo manipulation of bone marrow cells to rescue uremia-induced dysfunction for autologous therapy #MMPMID26062806 Grange C; Bussolati B Stem Cell Res Ther 2015[]; 6 (1): ä PMID26062806show ga Uremic toxins are known to affect the regenerative properties of tissue-resident and circulating stem cells and thus appear to be a limiting factor for autologous stem cell-based approaches for treating chronic kidney disease. The recent article by van Koppen and colleagues in Stem Cell Research & Therapy provides evidence that an ex vivo short-term pre-treatment with statins reverts the dysfunction of bone marrow stem cells isolated from rats with renal impairment. Indeed, statin pre-treated cells improved renal function in a model of established chronic kidney disease. Our commentary discusses the potential of this approach in the context of autologous cell therapy and the available knowledge on the mechanisms involved in uremia-induced stem cell dysfunction. äEx vivo manipulation of bone marrow cells to rescue uremia-induced dys(epmc).pdf DeepDyve Pubget Overpricing