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Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Acta+Crystallogr+F+Struct+Biol+Commun 2015 ; 71 (Pt 6): 710-7 Nephropedia Template TP
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Crystallization of interleukin-18 for structure-based inhibitor design #MMPMID26057800
Krumm B; Meng X; Xiang Y; Deng J
Acta Crystallogr F Struct Biol Commun 2015[Jun]; 71 (Pt 6): 710-7 PMID26057800show ga
Crystallization of apo interleukin-18 in low ionic strength conditions was achieved through surface-entropy reduction and rational protein design. Here, the design, expression, purification, crystallization, and structure determination of three apo interleukin-18 structures to between 1.9 and 2.85?Å resolution are reported.