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2015 ; 39
(3
): 230-7
Nephropedia Template TP
gab.com Text
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English Wikipedia
Detection of critical congenital heart defects: Review of contributions from
prenatal and newborn screening
#MMPMID25979782
Olney RS
; Ailes EC
; Sontag MK
Semin Perinatol
2015[Apr]; 39
(3
): 230-7
PMID25979782
show ga
In 2011, statewide newborn screening programs for critical congenital heart
defects began in the United States, and subsequently screening has been
implemented widely. In this review, we focus on data reports and collection
efforts related to both prenatal diagnosis and newborn screening.
Defect-specific, maternal, and geographic factors are associated with variations
in prenatal detection, so newborn screening provides a population-wide safety net
for early diagnosis. A new web-based repository is collecting information on
newborn screening program policies, quality indicators related to screening
programs, and specific case-level data on infants with these defects. Birth
defects surveillance programs also collect data about critical congenital heart
defects, particularly related to diagnostic timing, mortality, and services.
Individuals from state programs, federal agencies, and national organizations
will be interested in these data to further refine algorithms for screening in
normal newborn nurseries, neonatal intensive care settings, and other special
populations; and ultimately to evaluate the impact of screening on outcomes.