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10.1038/srep10953 http://scihub22266oqcxt.onion/10.1038/srep10953 C4460726!4460726!26055266     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2015 ; 5 (ä): ä Nephropedia Template TP {{tp|p=26055266|t=2015. Short Course Radiation in the Treatment of Localized Rectal cancer: A Systematic Review and Meta-Analysis |pdf=|usr=}}{{26055266}} gab.com Text Short Course Radiation in the Treatment of Localized Rectal cancer: A Systematic Review and Meta-Analysis JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26055266 #FOAvip This meta-analysis sets out to systematically assess the efficacy of short course radiation (SRT) for rectal cancer patients based on randomized, controlled trials. Eight randomized controlled trials involving 6894 patients were ultimately included in this meta-analysis. Three trials (n?=?2574) compared SRT with surgery alone. Local recurrence was improved (HR?=?0.48, 95% CI 0.40 to 0.58). Overall survival was marginally improved with an HR of 0.90 (95% CI 0.81 to 1.00), but the magnitude of benefit was heterogeneous across trials. An additional three trials (n?=?3682) compared SRT with selective postoperative radiation ± chemotherapy. A significant reduction of local recurrence (HR?=?0.44, 95% CI 0.35 to 0.56) was also found after SRT. However, no benefit in overall survival was observed. Moreover, two trials (n?=?638) compared SRT with long course chemoradiation. There was no statistically significant local recurrence or overall survival difference observed between the two strategies. Patients receiving SRT had lower grade 3 or 4 acute treatment related toxicity (RR 0.11, 95% CI 0.05 to 0.22) whereas no difference in late toxicity was observed. Overall, SRT is a reasonable alternative for resectable rectal cancer patients and should be part of an informed discussion of treatment options for this group of patients. Twit Text FOAVip Short Course Radiation in the Treatment of Localized Rectal cancer: A Systematic Review and Meta-Analysis ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26055266 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26055266 #FOAvip English Wikipedia <ref>{{Cite pmid|26055266}}</ref> Short Course Radiation in the Treatment of Localized Rectal cancer: A Systematic Review and Meta-Analysis #MMPMID26055266 Chen C; Sun P; Rong J; Weng HW; Dai Qs; Ye S Sci Rep 2015[]; 5 (ä): ä PMID26055266show ga This meta-analysis sets out to systematically assess the efficacy of short course radiation (SRT) for rectal cancer patients based on randomized, controlled trials. Eight randomized controlled trials involving 6894 patients were ultimately included in this meta-analysis. Three trials (n?=?2574) compared SRT with surgery alone. Local recurrence was improved (HR?=?0.48, 95% CI 0.40 to 0.58). Overall survival was marginally improved with an HR of 0.90 (95% CI 0.81 to 1.00), but the magnitude of benefit was heterogeneous across trials. An additional three trials (n?=?3682) compared SRT with selective postoperative radiation ± chemotherapy. A significant reduction of local recurrence (HR?=?0.44, 95% CI 0.35 to 0.56) was also found after SRT. However, no benefit in overall survival was observed. Moreover, two trials (n?=?638) compared SRT with long course chemoradiation. There was no statistically significant local recurrence or overall survival difference observed between the two strategies. Patients receiving SRT had lower grade 3 or 4 acute treatment related toxicity (RR 0.11, 95% CI 0.05 to 0.22) whereas no difference in late toxicity was observed. Overall, SRT is a reasonable alternative for resectable rectal cancer patients and should be part of an informed discussion of treatment options for this group of patients. äShort Course Radiation in the Treatment of Localized Rectal cancer: A (epmc).pdf DeepDyve Pubget Overpricing