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2015 ; 15 Suppl 1
(Suppl 1
): S8
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
A formal concept analysis and semantic query expansion cooperation to refine
health outcomes of interest
#MMPMID26043839
Curé OC
; Maurer H
; Shah NH
; Le Pendu P
BMC Med Inform Decis Mak
2015[]; 15 Suppl 1
(Suppl 1
): S8
PMID26043839
show ga
BACKGROUND: Electronic Health Records (EHRs) are frequently used by clinicians
and researchers to search for, extract, and analyze groups of patients by
defining Health Outcome of Interests (HOI). The definition of an HOI is generally
considered a complex and time consuming task for health care professionals.
METHODS: In our clinical note-based pharmacovigilance research, we often operate
upon potentially hundreds of ontologies at once, expand query inputs, and we also
increase the search space over clinical text as well as structured data. Such a
method implies to specify an initial set of seed concepts, which are based on
concept unique identifiers. This paper presents a novel method based on Formal
Concept Analysis (FCA) and Semantic Query Expansion (SQE) to assist the end-user
in defining their seed queries and in refining the expanded search space that it
encompasses. RESULTS: We evaluate our method over a gold-standard corpus from the
2008 i2b2 Obesity Challenge. This experimentation emphasizes positive results for
sensitivity and specificity measures. Our new approach provides better recall
with high precision of the obtained results. The most promising aspect of this
approach consists in the discovery of positive results not present our Obesity
NLP reference set. CONCLUSIONS: Together with a Web graphical user interface, our
FCA and SQE cooperation end up being an efficient approach for refining health
outcome of interest using plain terms. We consider that this approach can be
extended to support other domains such as cohort building tools.