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10.5853/jos.2015.17.2.127

http://scihub22266oqcxt.onion/10.5853/jos.2015.17.2.127
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C4460332!4460332!26060800
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suck abstract from ncbi


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pmid26060800      J+Stroke 2015 ; 17 (2): 127-37
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  • Evolution of Endovascular Therapy in Acute Stroke: Implications of Device Development #MMPMID26060800
  • Balasubramaian A; Mitchell P; Dowling R; Yan B
  • J Stroke 2015[May]; 17 (2): 127-37 PMID26060800show ga
  • Intravenous thrombolysis is an effective treatment for acute ischaemic stroke. However, vascular recanalization rates remain poor especially in the setting of large artery occlusion. On the other hand, endovascular intra-arterial therapy addresses this issue with superior recanalization rates compared with intravenous thrombolysis. Although previous randomized controlled studies of intra-arterial therapy failed to demonstrate superiority, the failings may be attributed to a combination of inferior intra-arterial devices and suboptimal selection criteria. The recent results of several randomized controlled trials have demonstrated significantly improved outcomes, underpinning the advantage of newer intra-arterial devices and superior recanalization rates, leading to renewed interest in establishing intra-arterial therapy as the gold standard for acute ischaemic stroke. The aim of this review is to outline the history and development of different intra-arterial devices and future directions in research.
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