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10.1182/blood-2014-11-575357 http://scihub22266oqcxt.onion/10.1182/blood-2014-11-575357 C4458796!4458796!25887776     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Blood 2015 ; 125 (23): 3536-41 Nephropedia Template TP {{tp|p=25887776|t=2015. Emerging EPO and EPO receptor regulators and signal transducers |pdf=|usr=}}{{25887776}} gab.com Text Emerging EPO and EPO receptor regulators and signal transducers JO: Blood http://www.kidney.de/pget.php?&tw=1&pmid=25887776 #FOAvip As essential mediators of red cell production, erythropoietin (EPO) and its cell surface receptor (EPO receptor [EPOR]) have been intensely studied. Early investigations defined basic mechanisms for hypoxia-inducible factor induction of EPO expression, and within erythroid progenitors EPOR engagement of canonical Janus kinase 2/signal transducer and activator of transcription 5 (JAK2/STAT5), rat sarcoma/mitogen-activated protein kinase/extracellular signal-regulated kinase (RAS/MEK/ERK), and phosphatidylinositol 3-kinase (PI3K) pathways. Contemporary genetic, bioinformatic, and proteomic approaches continue to uncover new clinically relevant modulators of EPO and EPOR expression, and EPO?s biological effects. This Spotlight review highlights such factors and their emerging roles during erythropoiesis and anemia. Twit Text FOAVip Emerging EPO and EPO receptor regulators and signal transducers ????Blood http://www.kidney.de/pget.php?&tw=1&pmid=25887776 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25887776 #FOAvip English Wikipedia <ref>{{Cite pmid|25887776}}</ref> Emerging EPO and EPO receptor regulators and signal transducers #MMPMID25887776 Kuhrt D; Wojchowski DM Blood 2015[Jun]; 125 (23): 3536-41 PMID25887776show ga As essential mediators of red cell production, erythropoietin (EPO) and its cell surface receptor (EPO receptor [EPOR]) have been intensely studied. Early investigations defined basic mechanisms for hypoxia-inducible factor induction of EPO expression, and within erythroid progenitors EPOR engagement of canonical Janus kinase 2/signal transducer and activator of transcription 5 (JAK2/STAT5), rat sarcoma/mitogen-activated protein kinase/extracellular signal-regulated kinase (RAS/MEK/ERK), and phosphatidylinositol 3-kinase (PI3K) pathways. Contemporary genetic, bioinformatic, and proteomic approaches continue to uncover new clinically relevant modulators of EPO and EPOR expression, and EPO?s biological effects. This Spotlight review highlights such factors and their emerging roles during erythropoiesis and anemia. äEmerging EPO and EPO receptor regulators and signal transducers (epmc).pdf DeepDyve Pubget Overpricing