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10.1155/2015/368736

http://scihub22266oqcxt.onion/10.1155/2015/368736
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C4458560!4458560!26101781
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suck abstract from ncbi


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pmid26101781      J+Immunol+Res 2015 ; 2015 (ä): ä
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  • Harnessing the Microbiome to Enhance Cancer Immunotherapy #MMPMID26101781
  • Nelson MH; Diven MA; Huff LW; Paulos CM
  • J Immunol Res 2015[]; 2015 (ä): ä PMID26101781show ga
  • The microbiota plays a key role in regulating the innate and adaptive immune system. Herein, we review the immunological aspects of the microbiota in tumor immunity in mice and man, with a focus on toll-like receptor (TLR) agonists, vaccines, checkpoint modulators, chemotherapy, and adoptive T cell transfer (ACT) therapies. We propose innovative treatments that may safely harness the microbiota to enhance T cell-based therapies in cancer patients. Finally, we highlight recent developments in tumor immunotherapy, particularly novel ways to modulate the microbiome and memory T cell responses to human malignancies.
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