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10.1093/eurheartj/ehv007

http://scihub22266oqcxt.onion/10.1093/eurheartj/ehv007
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C4458286!4458286!25660055
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suck abstract from ncbi


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pmid25660055      Eur+Heart+J 2015 ; 36 (22): 1405-14
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  • Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction #MMPMID25660055
  • Stakos DA; Kambas K; Konstantinidis T; Mitroulis I; Apostolidou E; Arelaki S; Tsironidou V; Giatromanolaki A; Skendros P; Konstantinides S; Ritis K
  • Eur Heart J 2015[Jun]; 36 (22): 1405-14 PMID25660055show ga
  • Neutrophils are involved in the pathophysiology of infracted coronary arteries in STEMI via NET structures. Platelets, activated by thrombin, are required for NET formation, while the integrity of NET scaffold contributes to the functionality of NET-bound TF. The blockage of NET formation or local neutralization of NET-mediated TF signalling constitutes candidate therapeutic targets.
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