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10.1016/j.biomaterials.2014.12.043 http://scihub22266oqcxt.onion/10.1016/j.biomaterials.2014.12.043 C4457539!4457539 !25682155     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25682155 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Biomaterials 2015 ; 47 (ä): 1-12 Nephropedia Template TP {{tp|p=25682155 |t=2015. Enhanced survival and engraftment of transplanted stem cells using growth factor sequestering hydrogels |pdf=|usr=}}{{25682155 }} gab.com Text Enhanced survival and engraftment of transplanted stem cells using growth factor sequestering hydrogels JO: Biomaterials http://www.kidney.de/pget.php?&tw=1&pmid=25682155 #FOAvip We have generated a bioinspired tunable system of hyaluronic acid (HyA)-based hydrogels for Matrix-Assisted Cell Transplantation (MACT). With this material, we have independently evaluated matrix parameters such as adhesion peptide density, mechanical properties, and growth factor sequestering capacity, to engineer an environment that imbues donor cells with a milieu that promotes survival and engraftment with host tissues after transplantation. Using a versatile population of Sca-1(+)/CD45(-) cardiac progenitor cells (CPCs), we demonstrated that the addition of heparin in the HyA hydrogels was necessary to coordinate the presentation of TGF?1 and to support the trophic functions of the CPCs via endothelial cell differentiation and vascular like tubular network formation. Presentation of exogenous TGF?1 by binding with heparin improved differentiated CPC function by sequestering additional endogenously-produced angiogenic factors. Finally, we demonstrated that TGF?1 and heparin-containing HyA hydrogels can promote CPC survival when implanted subcutaneously into murine hind-limbs and encouraged their participation in the ensuing neovascular response, which included blood vessels that had anastomosed with the host's blood vessels. Twit Text FOAVip Enhanced survival and engraftment of transplanted stem cells using growth factor sequestering hydrogels ????Biomaterials http://www.kidney.de/pget.php?&tw=1&pmid=25682155 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25682155 #FOAvip English Wikipedia <ref>{{Cite pmid|25682155 }}</ref> Enhanced survival and engraftment of transplanted stem cells using growth factor sequestering hydrogels #MMPMID25682155 Jha AK ; Tharp KM ; Ye J ; Santiago-Ortiz JL ; Jackson WM ; Stahl A ; Schaffer DV ; Yeghiazarians Y ; Healy KE Biomaterials 2015[Apr]; 47 (ä): 1-12 PMID25682155 show ga We have generated a bioinspired tunable system of hyaluronic acid (HyA)-based hydrogels for Matrix-Assisted Cell Transplantation (MACT). With this material, we have independently evaluated matrix parameters such as adhesion peptide density, mechanical properties, and growth factor sequestering capacity, to engineer an environment that imbues donor cells with a milieu that promotes survival and engraftment with host tissues after transplantation. Using a versatile population of Sca-1(+)/CD45(-) cardiac progenitor cells (CPCs), we demonstrated that the addition of heparin in the HyA hydrogels was necessary to coordinate the presentation of TGF?1 and to support the trophic functions of the CPCs via endothelial cell differentiation and vascular like tubular network formation. Presentation of exogenous TGF?1 by binding with heparin improved differentiated CPC function by sequestering additional endogenously-produced angiogenic factors. Finally, we demonstrated that TGF?1 and heparin-containing HyA hydrogels can promote CPC survival when implanted subcutaneously into murine hind-limbs and encouraged their participation in the ensuing neovascular response, which included blood vessels that had anastomosed with the host's blood vessels. |*Stem Cell Transplantation [MESH] |Animals [MESH] |Binding Sites [MESH] |Biocompatible Materials/chemistry [MESH] |Cell Adhesion [MESH] |Cell Differentiation [MESH] |Cell Proliferation [MESH] |Cell Survival [MESH] |Heparin/chemistry [MESH] |Hyaluronic Acid/chemistry [MESH] |Hydrogels/*chemistry [MESH] |Intercellular Signaling Peptides and Proteins/*metabolism [MESH] |Mice [MESH] |Neovascularization, Pathologic [MESH] |Peptides/chemistry [MESH] |Stem Cells/*cytology [MESH] |Stress, Mechanical [MESH] |Sulfhydryl Compounds/chemistry [MESH]Enhanced survival and engraftment of transplanted stem cells using gro(epmc).pdf DeepDyve Pubget Overpricing