Kleinstein RN; Sinnott LT; Jones-Jordan LA; Sims J; Zadnik K
Arch Ophthalmol 2012[Oct]; 130 (10): 1274-9 PMID22688326show ga
Objective: To report the percentage of new cases of myopia in 4,927 children, age 5 - 16 years, who participated in the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study between 1989 and 2009. Design: A multicenter, longitudinal, observational, volunteer study of refractive error and ocular development in children from five ethnic/racial groups. Methods: Subjects were children who were not myopic (right eye?s cycloplegic autorefraction of less myopia/more hyperopoia than ?0.75 D in both principal meridians) at study entry. A new case was a diagnosis of myopia (right eye?s cycloplegic autorefraction of ?0.75 D or more myopia in both principal meridians) after study entry. Results: Among the 4,556 children entering the study as not myopic, 749 (16.4%) were diagnosed as myopic after study entry. Among the 749, the age of diagnosis varied from 7 to 16 years, with the largest number, 136 (18.2%), diagnosed at age 11 years. New cases of myopia occurred in 27.3% of Asians, 21.4% of Hispanics, 14.5% of Native Americans, 13.9% of African Americans, and 11% of Whites. Females had more new cases, 18.5%, than males, 14.5%. Normal birth weight children had more new cases (16.9%), than low birth weight, (15.5%). Conclusions: Sixteen percent of children enrolled in the CLEERE Study developed myopia during their school-age years. The percentage increased yearly until age 11 years, after which it decreased. New cases of myopia varied by ethnic/racial group.