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http://scihub22266oqcxt.onion/ C4457449!4457449!18508521     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Biosci 2008 ; 13 (ä): 4426-50 Nephropedia Template TP {{tp|p=18508521|t=2008. The diverse functions of Src family kinases in macrophages |pdf=|usr=}}{{18508521}} gab.com Text The diverse functions of Src family kinases in macrophages JO: Front Biosci http://www.kidney.de/pget.php?&tw=1&pmid=18508521 #FOAvip Macrophages are key components of the innate immune response. These cells possess a diverse repertoire of receptors that allow them to respond to a host of external stimuli including cytokines, chemokines, and pathogen-associated molecules. Signals resulting from these stimuli activate a number of macrophage functional responses such as adhesion, migration, phagocytosis, proliferation, survival, cytokine release and production of reactive oxygen and nitrogen species. The cytoplasmic tyrosine kinase Src and its family members (SFKs) have been implicated in many intracellular signaling pathways in macrophages, initiated by a diverse set of receptors ranging from integrins to Toll-like receptors. However, it has been difficult to implicate any given member of the family in any specific pathway. SFKs appear to have overlapping and complementary functions in many pathways. Perhaps the function of these enzymes is to modulate the overall intracellular signaling network in macrophages, rather than operating as exclusive signaling switches for defined pathways. In general, SFKs may function more like rheostats, influencing the amplitude of many pathways. Twit Text FOAVip The diverse functions of Src family kinases in macrophages ????Front Biosci http://www.kidney.de/pget.php?&tw=1&pmid=18508521 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18508521 #FOAvip English Wikipedia <ref>{{Cite pmid|18508521}}</ref> The diverse functions of Src family kinases in macrophages #MMPMID18508521 Abram CL; Lowell CA Front Biosci 2008[]; 13 (ä): 4426-50 PMID18508521show ga Macrophages are key components of the innate immune response. These cells possess a diverse repertoire of receptors that allow them to respond to a host of external stimuli including cytokines, chemokines, and pathogen-associated molecules. Signals resulting from these stimuli activate a number of macrophage functional responses such as adhesion, migration, phagocytosis, proliferation, survival, cytokine release and production of reactive oxygen and nitrogen species. The cytoplasmic tyrosine kinase Src and its family members (SFKs) have been implicated in many intracellular signaling pathways in macrophages, initiated by a diverse set of receptors ranging from integrins to Toll-like receptors. However, it has been difficult to implicate any given member of the family in any specific pathway. SFKs appear to have overlapping and complementary functions in many pathways. Perhaps the function of these enzymes is to modulate the overall intracellular signaling network in macrophages, rather than operating as exclusive signaling switches for defined pathways. In general, SFKs may function more like rheostats, influencing the amplitude of many pathways. äThe diverse functions of Src family kinases in macrophages (epmc).pdf DeepDyve Pubget Overpricing