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10.1038/srep10917

http://scihub22266oqcxt.onion/10.1038/srep10917
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C4456939!4456939!26047021
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suck abstract from ncbi


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pmid26047021      Sci+Rep 2015 ; 5 (ä): ä
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  • An effective plasma membrane proteomics approach for small tissue samples #MMPMID26047021
  • Smolders K; Lombaert N; Valkenborg D; Baggerman G; Arckens L
  • Sci Rep 2015[]; 5 (ä): ä PMID26047021show ga
  • Advancing the quest for new drug targets demands the development of innovative plasma membrane proteome research strategies applicable to small, functionally defined tissue samples. Biotinylation of acute tissue slices and streptavidin pull-down followed by shotgun proteomics allowed the selective extraction and identification of >1,600 proteins of which >60% are associated with the plasma membrane, including (G-protein coupled) receptors, ion channels and transporters, and this from mm3-scale tissue.
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