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10.1128/JB.02516-14

http://scihub22266oqcxt.onion/10.1128/JB.02516-14
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C4455261!4455261!25825428
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suck abstract from ncbi


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pmid25825428      J+Bacteriol 2015 ; 197 (13): 2092-103
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  • The Matrix Reloaded: How Sensing the Extracellular Matrix Synchronizes Bacterial Communities #MMPMID25825428
  • Steinberg N; Kolodkin-Gal I
  • J Bacteriol 2015[Jul]; 197 (13): 2092-103 PMID25825428show ga
  • In response to chemical communication, bacterial cells often organize themselves into complex multicellular communities that carry out specialized tasks. These communities are frequently referred to as biofilms, which involve the collective behavior of different cell types. Like cells of multicellular eukaryotes, the biofilm cells are surrounded by self-produced polymers that constitute the extracellular matrix (ECM), which binds them to each other and to the surface. In multicellular eukaryotes, it has been evident for decades that cell-ECM interactions control multiple cellular processes during development. While cells both in biofilms and in multicellular eukaryotes are surrounded by ECM and activate various genetic programs, until recently it has been unclear whether cell-ECM interactions are recruited in bacterial communicative behaviors. In this review, we describe the examples reported thus far for ECM involvement in control of cell behavior throughout the different stages of biofilm formation. The studies presented in this review have provided a newly emerging perspective of the bacterial ECM as an active player in regulation of biofilm development.
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