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10.2215/CJN.05160514 http://scihub22266oqcxt.onion/10.2215/CJN.05160514 C4455206!4455206!25941194     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+J+Am+Soc+Nephrol 2015 ; 10 (6): 983-93 Nephropedia Template TP {{tp|p=25941194|t=2015. Dialysis Modality and Mortality in the Elderly: A Meta-Analysis |pdf=|usr=}}{{25941194}} gab.com Text Dialysis Modality and Mortality in the Elderly: A Meta-Analysis JO: Clin J Am Soc Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=25941194 #FOAvip Background and objectives: Identifying the appropriate choice between hemodialysis (HD) and peritoneal dialysis (PD) is an unresolved issue in elderly patients with ESRD, who are at high risk for death but have a low chance of receiving kidney transplantation. Design, setting, participants, & measurements: Data on 13,065 incident dialysis Korean patients (age?65 years) receiving HD (n=10,675) or PD (n=2390) were obtained from the Korean Health Insurance dataset. Multiple statistical approaches, including the multivariate Cox model, were used to compare mortality between Korean patients receiving PD and those receiving HD. Subsequently, meta-analysis of previous comparison studies (published since the year 2000; population-based studies) and the Korean dataset was performed. Results: During a mean duration of 1.8±1.3 years (maximum of 5 years), the Korean PD group had a higher mortality rate than the Korean HD group (hazard ratio [HR], 1.20 [95% confidence interval (95% CI), 1.13 to 1.28]; P<0.001 by multivariate Cox model). The discrepancy between the two modalities was greater in the presence of certain conditions, such as diabetes mellitus or longer dialysis duration. In the meta-analysis, 15 studies involving >631,421 elderly patients were reviewed. Compared with HD, the pooled HR with PD was 1.10 (95% CI, 1.01 to 1.20). When the meta-analysis was stratified by confounding factors, the survival benefit from HD was particularly strong in subgroups that had diabetes mellitus, had long dialysis duration (>1 year), or contained cohorts starting dialysis in the 1990s. Conclusions: A meta-analysis that included results in Korean patients suggests a higher risk for death in elderly patients receiving PD than in those receiving HD. Twit Text FOAVip Dialysis Modality and Mortality in the Elderly: A Meta-Analysis ????Clin J Am Soc Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=25941194 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25941194 #FOAvip English Wikipedia <ref>{{Cite pmid|25941194}}</ref> Dialysis Modality and Mortality in the Elderly: A Meta-Analysis #MMPMID25941194 Han SS; Park JY; Kang S; Kim KH; Ryu DR; Kim H; Joo KW; Lim CS; Kim YS; Kim DK Clin J Am Soc Nephrol 2015[Jun]; 10 (6): 983-93 PMID25941194show ga Background and objectives: Identifying the appropriate choice between hemodialysis (HD) and peritoneal dialysis (PD) is an unresolved issue in elderly patients with ESRD, who are at high risk for death but have a low chance of receiving kidney transplantation. Design, setting, participants, & measurements: Data on 13,065 incident dialysis Korean patients (age?65 years) receiving HD (n=10,675) or PD (n=2390) were obtained from the Korean Health Insurance dataset. Multiple statistical approaches, including the multivariate Cox model, were used to compare mortality between Korean patients receiving PD and those receiving HD. Subsequently, meta-analysis of previous comparison studies (published since the year 2000; population-based studies) and the Korean dataset was performed. Results: During a mean duration of 1.8±1.3 years (maximum of 5 years), the Korean PD group had a higher mortality rate than the Korean HD group (hazard ratio [HR], 1.20 [95% confidence interval (95% CI), 1.13 to 1.28]; P<0.001 by multivariate Cox model). The discrepancy between the two modalities was greater in the presence of certain conditions, such as diabetes mellitus or longer dialysis duration. In the meta-analysis, 15 studies involving >631,421 elderly patients were reviewed. Compared with HD, the pooled HR with PD was 1.10 (95% CI, 1.01 to 1.20). When the meta-analysis was stratified by confounding factors, the survival benefit from HD was particularly strong in subgroups that had diabetes mellitus, had long dialysis duration (>1 year), or contained cohorts starting dialysis in the 1990s. Conclusions: A meta-analysis that included results in Korean patients suggests a higher risk for death in elderly patients receiving PD than in those receiving HD. äDialysis Modality and Mortality in the Elderly: A Meta-Analysis (epmc).pdf DeepDyve Pubget Overpricing