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10.1155/2015/482171 http://scihub22266oqcxt.onion/10.1155/2015/482171 C4454760!4454760!26089917     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Stem+Cells+Int 2015 ; 2015 (ä): ä Nephropedia Template TP {{tp|p=26089917|t=2015. Exosomes for Intramyocardial Intercellular Communication |pdf=|usr=}}{{26089917}} gab.com Text Exosomes for Intramyocardial Intercellular Communication JO: Stem Cells Int http://www.kidney.de/pget.php?&tw=1&pmid=26089917 #FOAvip Cross-talk between different cell types plays central roles both in cardiac homeostasis and in adaptive responses of the heart to stress. Cardiomyocytes (CMs) send biological messages to the other cell types present in the heart including endothelial cells (ECs) and fibroblasts. In turn, CMs receive messages from these cells. Recent evidence has now established that exosomes, nanosized secreted extracellular vesicles, are crucial mediators of such messages. CMs, ECs, cardiac fibroblasts, and cardiac progenitor cells (CPCs) release exosomes carrying nonrandom subsets of proteins, lipids, and nucleic acids present in their cells of origin. Exosomes secreted from CMs are internalized by fibroblasts and regulate gene expression in these cells as well as in ECs. CPC-derived exosomes protect CMs against apoptosis while also stimulating angiogenesis. They are rich in cardioprotective and proangiogenic microRNAs such as miR-146, miR-210, and miR-132. When injected into infracted hearts in vivo, CPC-derived exosomes reduce infarct size and improve cardiac function. Thus, exosomes are emerging both as key mediators of intercellular communication in the heart and as therapeutic candidates for heart disease. Twit Text FOAVip Exosomes for Intramyocardial Intercellular Communication ????Stem Cells Int http://www.kidney.de/pget.php?&tw=1&pmid=26089917 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26089917 #FOAvip English Wikipedia <ref>{{Cite pmid|26089917}}</ref> Exosomes for Intramyocardial Intercellular Communication #MMPMID26089917 Cervio E; Barile L; Moccetti T; Vassalli G Stem Cells Int 2015[]; 2015 (ä): ä PMID26089917show ga Cross-talk between different cell types plays central roles both in cardiac homeostasis and in adaptive responses of the heart to stress. Cardiomyocytes (CMs) send biological messages to the other cell types present in the heart including endothelial cells (ECs) and fibroblasts. In turn, CMs receive messages from these cells. Recent evidence has now established that exosomes, nanosized secreted extracellular vesicles, are crucial mediators of such messages. CMs, ECs, cardiac fibroblasts, and cardiac progenitor cells (CPCs) release exosomes carrying nonrandom subsets of proteins, lipids, and nucleic acids present in their cells of origin. Exosomes secreted from CMs are internalized by fibroblasts and regulate gene expression in these cells as well as in ECs. CPC-derived exosomes protect CMs against apoptosis while also stimulating angiogenesis. They are rich in cardioprotective and proangiogenic microRNAs such as miR-146, miR-210, and miR-132. When injected into infracted hearts in vivo, CPC-derived exosomes reduce infarct size and improve cardiac function. Thus, exosomes are emerging both as key mediators of intercellular communication in the heart and as therapeutic candidates for heart disease. äExosomes for Intramyocardial Intercellular Communication (epmc).pdf DeepDyve Pubget Overpricing