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2014 ; 111
(9
): 1814-23
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Updated investigations of cancer excesses in individuals born or resident in the
vicinity of Sellafield and Dounreay
#MMPMID25051410
Bunch KJ
; Vincent TJ
; Black RJ
; Pearce MS
; McNally RJ
; McKinney PA
; Parker L
; Craft AW
; Murphy MF
Br J Cancer
2014[Oct]; 111
(9
): 1814-23
PMID25051410
show ga
BACKGROUND: Earlier studies have shown raised risks of leukaemia and non-Hodgkin
lymphoma in children, teenagers and young adults resident either at birth or
diagnosis in Seascale. Some increases in cancer risk in these age groups have
also been noted among those living around Dounreay. We aimed to update previous
analyses relating to areas close to these nuclear installations by considering
data from an additional 16 years of follow-up. METHODS: Cross-sectional analyses
compared cancer incidence rates for 1963-2006 among those aged 0-24 years at
diagnosis living in geographically specified areas around either Sellafield or
Dounreay with general population rates. Cancer incidence for the period 1971-2006
among the cohort of Cumbrian births between 1950 and 2006 was compared to
national incidence for 1971-2006 using person-years analysis. Cancer among those
born in the postcode sector closest to Dounreay was compared with that among
those born in the three adjoining postcode sectors. Analyses considered both
cancer overall and ICD-O-3 defined diagnostic subgroups including leukaemia,
central nervous system tumours and other malignancies. RESULTS: Apart from
previously reported raised risks, no new significantly increased risks for cancer
overall or any diagnostic subgroup were found among children or teenagers and
young adults living around either nuclear installation. Individuals born close to
the installations from 1950 to 2006 were not shown to be at any increased risk of
cancer during the period 1971 to date. CONCLUSIONS: Analysis of recent data
suggests that children, teenagers and young adults currently living close to
Sellafield and Dounreay are not at an increased risk of developing cancer.
Equally, there is no evidence of any increased cancer risk later in life among
those resident in these areas at birth.