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10.1136/bmj.h2388 http://scihub22266oqcxt.onion/10.1136/bmj.h2388 C4452930!4452930 !26037950     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26037950 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMJ 2015 ; 350 (ä): h2388 Nephropedia Template TP {{tp|p=26037950 |t=2015. Varenicline and risk of psychiatric conditions, suicidal behaviour, criminal offending, and transport accidents and offences: population based cohort study |pdf=|usr=}}{{26037950 }} gab.com Text Varenicline and risk of psychiatric conditions, suicidal behaviour, criminal offending, and transport accidents and offences: population based cohort study JO: BMJ http://www.kidney.de/pget.php?&tw=1&pmid=26037950 #FOAvip OBJECTIVE: To examine associations between varenicline and the incidence of a range of adverse outcomes. DESIGN: Population based cohort study using within person analyses to control for confounding by indication. SETTING: Whole population of Sweden. PARTICIPANTS: 7,917,436 people aged 15 and over, of whom 69,757 were treated with varenicline between 2006 and 2009. MAIN OUTCOME MEASURES: Incidence of new psychiatric conditions, suicidal behaviour, suspected and convicted criminal offending, transport accidents, and suspected and convicted traffic offences. RESULTS: In the whole population, 337,393 new psychiatric conditions were diagnosed during follow-up. In addition, 507,823 suspected and 338,608 convicted crimes, 40,595 suicidal events, 124,445 transport accidents, and 99,895 suspected and 57,068 convicted traffic crimes were recorded. Within person analyses showed that varenicline was not associated with significant hazards of suicidal behaviour, criminal offending, transport accidents, traffic offences, or psychoses. However, varenicline was associated with a small increase in the risk of anxiety conditions (hazard ratio 1.23, 95% confidence interval 1.01 to 1.51) and mood conditions (1.31, 1.06 to 1.63), which was only seen in people with pre-existing psychiatric disorders. CONCLUSIONS: Concerns that varenicline is associated with an increased risk of many adverse outcomes, including suicidality and accidents, are not supported in this observational study. The small increase in risk of two psychiatric conditions in people with pre-existing psychiatric disorders needs to be confirmed using other research designs. Twit Text FOAVip Varenicline and risk of psychiatric conditions, suicidal behaviour, criminal offending, and transport accidents and offences: population based cohort study ????BMJ http://www.kidney.de/pget.php?&tw=1&pmid=26037950 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26037950 #FOAvip English Wikipedia <ref>{{Cite pmid|26037950 }}</ref> Varenicline and risk of psychiatric conditions, suicidal behaviour, criminal offending, and transport accidents and offences: population based cohort study #MMPMID26037950 Molero Y ; Lichtenstein P ; Zetterqvist J ; Gumpert CH ; Fazel S BMJ 2015[Jun]; 350 (ä): h2388 PMID26037950 show ga OBJECTIVE: To examine associations between varenicline and the incidence of a range of adverse outcomes. DESIGN: Population based cohort study using within person analyses to control for confounding by indication. SETTING: Whole population of Sweden. PARTICIPANTS: 7,917,436 people aged 15 and over, of whom 69,757 were treated with varenicline between 2006 and 2009. MAIN OUTCOME MEASURES: Incidence of new psychiatric conditions, suicidal behaviour, suspected and convicted criminal offending, transport accidents, and suspected and convicted traffic offences. RESULTS: In the whole population, 337,393 new psychiatric conditions were diagnosed during follow-up. In addition, 507,823 suspected and 338,608 convicted crimes, 40,595 suicidal events, 124,445 transport accidents, and 99,895 suspected and 57,068 convicted traffic crimes were recorded. Within person analyses showed that varenicline was not associated with significant hazards of suicidal behaviour, criminal offending, transport accidents, traffic offences, or psychoses. However, varenicline was associated with a small increase in the risk of anxiety conditions (hazard ratio 1.23, 95% confidence interval 1.01 to 1.51) and mood conditions (1.31, 1.06 to 1.63), which was only seen in people with pre-existing psychiatric disorders. CONCLUSIONS: Concerns that varenicline is associated with an increased risk of many adverse outcomes, including suicidality and accidents, are not supported in this observational study. The small increase in risk of two psychiatric conditions in people with pre-existing psychiatric disorders needs to be confirmed using other research designs. |Accidents, Traffic/*statistics & numerical data [MESH] |Adolescent [MESH] |Adult [MESH] |Aged [MESH] |Benzazepines/*adverse effects [MESH] |Cohort Studies [MESH] |Crime/*statistics & numerical data [MESH] |Epidemiologic Methods [MESH] |Female [MESH] |Humans [MESH] |Male [MESH] |Mental Disorders/*chemically induced [MESH] |Middle Aged [MESH] |Nicotinic Agonists/*adverse effects [MESH] |Quinoxalines/*adverse effects [MESH] |Smoking Cessation/statistics & numerical data [MESH] |Smoking Prevention [MESH] |Smoking/epidemiology [MESH] |Substance Withdrawal Syndrome/epidemiology/etiology [MESH] |Suicide/*statistics & numerical data [MESH] |Tobacco Use Cessation Devices/adverse effects/statistics & numerical data [MESH] |Varenicline [MESH]Varenicline and risk of psychiatric conditions, suicidal behaviour, cr(epmc).pdf DeepDyve Pubget Overpricing