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10.1155/2015/374178

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suck abstract from ncbi


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pmid26078978
      J+Diabetes+Res 2015 ; 2015 (ä): 374178
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  • Vitamin D Deficiency Is Associated with the Presence and Severity of Diabetic Retinopathy in Type 2 Diabetes Mellitus #MMPMID26078978
  • Alcubierre N ; Valls J ; Rubinat E ; Cao G ; Esquerda A ; Traveset A ; Granado-Casas M ; Jurjo C ; Mauricio D
  • J Diabetes Res 2015[]; 2015 (ä): 374178 PMID26078978 show ga
  • There is very few evidences on the role of vitamin D in the development of diabetic retinopathy. The aim of the current study was to explore whether there is an association of vitamin D status and diabetic retinopathy in type 2 diabetes. Two groups of patients were selected: 139 and 144 patients with and without retinopathy, respectively, as assessed by an experienced ophthalmologist. Subjects with advanced late diabetic complications were excluded to avoid confounding biases. 25-Hydroxy-vitamin D3 (25(OH)D) concentrations and vitamin D deficiency were associated with the presence of diabetic retinopathy. Additionally, patients with more advanced stages of retinopathy (grades 2-4) had lower concentrations of 25(OH)D and were more frequently vitamin D deficient as compared with patients not carrying this eye complication. In conclusion, our study confirms the association of vitamin D deficiency with the presence and severity of diabetic retinopathy in type 2 diabetes. Further experimental and prospective studies on this issue are clearly warranted.
  • |Aged [MESH]
  • |Calcifediol/blood [MESH]
  • |Case-Control Studies [MESH]
  • |Cross-Sectional Studies [MESH]
  • |Diabetes Mellitus, Type 2/blood/*complications [MESH]
  • |Diabetic Retinopathy/*complications/epidemiology/etiology/physiopathology [MESH]
  • |Female [MESH]
  • |Hospitals, University [MESH]
  • |Humans [MESH]
  • |Linear Models [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Nutritional Status [MESH]
  • |Prevalence [MESH]
  • |Risk [MESH]
  • |Severity of Illness Index [MESH]
  • |Spain/epidemiology [MESH]
  • |Tertiary Care Centers [MESH]


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