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10.1155/2015/759610 http://scihub22266oqcxt.onion/10.1155/2015/759610 C4452098!4452098 !26090499     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26090499 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Immunol+Res 2015 ; 2015 (ä): 759610 Nephropedia Template TP {{tp|p=26090499 |t=2015. Methotrexate, Cyclosporine A, and Biologics Protect against Atherosclerosis in Rheumatoid Arthritis |pdf=|usr=}}{{26090499 }} gab.com Text Methotrexate, Cyclosporine A, and Biologics Protect against Atherosclerosis in Rheumatoid Arthritis JO: J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=26090499 #FOAvip INTRODUCTION: The risk of cardiovascular disease is increased in rheumatoid arthritis (RA). A meta-analysis showed increased intima media thickness (IMT) in RA. It has been shown that disease modifying antirheumatic drugs (DMARDs) may influence the progression of atherosclerosis. However, it was suggested that biologics may be more efficient than other DMARDs (including methotrexate--MTX) in protecting against atherosclerosis. OBJECTIVES: The aim of this study was to assess the influence of different RA characteristics and treatment regimens on IMT and atherosclerotic plaques. PATIENTS AND METHODS: 317 RA patients and 111 controls were included in the study. IMT was measured in carotid (CIMT) and femoral (FIMT) arteries. Arteries were screened for the presence of plaques. RESULTS: CIMT, FIMT, and prevalence of plaques were lower in patients treated with methotrexate (MTX) ? 20 mg/wk, cyclosporine (CsA), or biologics than in patients treated with lower doses of MTX and other disease modifying antirheumatic drugs. No differences in IMT between patients treated with MTX ? 20 mg/wk, biologics, or CsA were found. CONCLUSIONS: We found a beneficial effect of MTX ? 20 mg/wk, biologics, and CsA on atherosclerosis. We do not confirm a stronger influence of biologics on IMT compared with therapeutic doses of MTX. Twit Text FOAVip Methotrexate, Cyclosporine A, and Biologics Protect against Atherosclerosis in Rheumatoid Arthritis ????J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=26090499 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26090499 #FOAvip English Wikipedia <ref>{{Cite pmid|26090499 }}</ref> Methotrexate, Cyclosporine A, and Biologics Protect against Atherosclerosis in Rheumatoid Arthritis #MMPMID26090499 Kisiel B ; Kruszewski R ; Juszkiewicz A ; Raczkiewicz A ; Bachta A ; T?ustochowicz M ; Staniszewska-Varga J ; K?os K ; Duda K ; Bogus?awska-Walecka R ; P?oski R ; T?ustochowicz W J Immunol Res 2015[]; 2015 (ä): 759610 PMID26090499 show ga INTRODUCTION: The risk of cardiovascular disease is increased in rheumatoid arthritis (RA). A meta-analysis showed increased intima media thickness (IMT) in RA. It has been shown that disease modifying antirheumatic drugs (DMARDs) may influence the progression of atherosclerosis. However, it was suggested that biologics may be more efficient than other DMARDs (including methotrexate--MTX) in protecting against atherosclerosis. OBJECTIVES: The aim of this study was to assess the influence of different RA characteristics and treatment regimens on IMT and atherosclerotic plaques. PATIENTS AND METHODS: 317 RA patients and 111 controls were included in the study. IMT was measured in carotid (CIMT) and femoral (FIMT) arteries. Arteries were screened for the presence of plaques. RESULTS: CIMT, FIMT, and prevalence of plaques were lower in patients treated with methotrexate (MTX) ? 20 mg/wk, cyclosporine (CsA), or biologics than in patients treated with lower doses of MTX and other disease modifying antirheumatic drugs. No differences in IMT between patients treated with MTX ? 20 mg/wk, biologics, or CsA were found. CONCLUSIONS: We found a beneficial effect of MTX ? 20 mg/wk, biologics, and CsA on atherosclerosis. We do not confirm a stronger influence of biologics on IMT compared with therapeutic doses of MTX. |Antirheumatic Agents/*therapeutic use [MESH] |Arthritis, Rheumatoid/*complications/pathology [MESH] |Atherosclerosis/*drug therapy/*etiology [MESH] |Biological Products/*therapeutic use [MESH] |Carotid Intima-Media Thickness [MESH] |Case-Control Studies [MESH] |Cyclosporine/*therapeutic use [MESH] |Disease Progression [MESH] |Female [MESH] |Humans [MESH] |Male [MESH] |Methotrexate/*therapeutic use [MESH] |Middle Aged [MESH] |Prevalence [MESH]Methotrexate, Cyclosporine A, and Biologics Protect against Atheroscle(epmc).pdf DeepDyve Pubget Overpricing