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10.3389/fcimb.2015.00049 http://scihub22266oqcxt.onion/10.3389/fcimb.2015.00049 C4451423!4451423!26082897     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Cell+Infect+Microbiol 2015 ; 5 (ä): ä Nephropedia Template TP {{tp|p=26082897|t=2015. Autophagy in Mycobacterium tuberculosis and HIV infections |pdf=|usr=}}{{26082897}} gab.com Text Autophagy in Mycobacterium tuberculosis and HIV infections JO: Front Cell Infect Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=26082897 #FOAvip Human Immunodeficiency Virus (HIV) and Mycobacterium tuberculosis (M.tb) are among the most lethal human pathogens worldwide, each being responsible for around 1.5 million deaths annually. Moreover, synergy between acquired immune deficiency syndrome (AIDS) and tuberculosis (TB) has turned HIV/M.tb co-infection into a major public health threat in developing countries. In the past decade, autophagy, a lysosomal catabolic process, has emerged as a major host immune defense mechanism against infectious agents like M.tb and HIV. Nevertheless, in some instances, autophagy machinery appears to be instrumental for HIV infection. Finally, there is mounting evidence that both pathogens deploy various countermeasures to thwart autophagy. This mini-review proposes an overview of the roles and regulations of autophagy in HIV and M.tb infections with an emphasis on microbial factors. We also discuss the role of autophagy manipulation in the context of HIV/M.tb co-infection. In future, a comprehensive understanding of autophagy interaction with these pathogens will be critical for development of autophagy-based prophylactic and therapeutic interventions for AIDS and TB. Twit Text FOAVip Autophagy in Mycobacterium tuberculosis and HIV infections ????Front Cell Infect Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=26082897 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26082897 #FOAvip English Wikipedia <ref>{{Cite pmid|26082897}}</ref> Autophagy in Mycobacterium tuberculosis and HIV infections #MMPMID26082897 Espert L; Beaumelle B; Vergne I Front Cell Infect Microbiol 2015[]; 5 (ä): ä PMID26082897show ga Human Immunodeficiency Virus (HIV) and Mycobacterium tuberculosis (M.tb) are among the most lethal human pathogens worldwide, each being responsible for around 1.5 million deaths annually. Moreover, synergy between acquired immune deficiency syndrome (AIDS) and tuberculosis (TB) has turned HIV/M.tb co-infection into a major public health threat in developing countries. In the past decade, autophagy, a lysosomal catabolic process, has emerged as a major host immune defense mechanism against infectious agents like M.tb and HIV. Nevertheless, in some instances, autophagy machinery appears to be instrumental for HIV infection. Finally, there is mounting evidence that both pathogens deploy various countermeasures to thwart autophagy. This mini-review proposes an overview of the roles and regulations of autophagy in HIV and M.tb infections with an emphasis on microbial factors. We also discuss the role of autophagy manipulation in the context of HIV/M.tb co-infection. In future, a comprehensive understanding of autophagy interaction with these pathogens will be critical for development of autophagy-based prophylactic and therapeutic interventions for AIDS and TB. äAutophagy in Mycobacterium tuberculosis and HIV infections (epmc).pdf DeepDyve Pubget Overpricing