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10.1084/jem.20142318 http://scihub22266oqcxt.onion/10.1084/jem.20142318 C4451136!4451136 !25964371     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25964371 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Exp+Med 2015 ; 212 (6 ): 865-74 Nephropedia Template TP {{tp|p=25964371 |t=2015. The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development |pdf=|usr=}}{{25964371 }} gab.com Text The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development JO: J Exp Med http://www.kidney.de/pget.php?&tw=1&pmid=25964371 #FOAvip Group 2 innate lymphoid cells (ILCs), or ILC2s, are a subset of recently identified ILCs, which play important roles in innate immunity by producing type 2 effector cytokines. Several transcription factors have been found to have critical functions in the development of both ILC2s and T cells. We report here that Bcl11b, a transcription factor essential in T cell lineage commitment and maintenance, is specifically expressed in progenitors committed to the ILC2 lineage and is required for ILC2 development. The Bcl11b gene is expressed in ?28% of ILC progenitors (ILCPs; common helper innate lymphoid progenitors or ILCPs expressing either ID2 or promyelocytic leukemia zinc finger, respectively). Both in vitro and in vivo, these Bcl11b-expressing early ILCPs generate only ILC2s. Inactivation of Bcl11b causes a complete loss of ILC2 development from hematopoietic progenitors, which is confirmed upon immune challenge with either papain administration or influenza virus infection. Twit Text FOAVip The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development ????J Exp Med http://www.kidney.de/pget.php?&tw=1&pmid=25964371 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25964371 #FOAvip English Wikipedia <ref>{{Cite pmid|25964371 }}</ref> The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development #MMPMID25964371 Yu Y ; Wang C ; Clare S ; Wang J ; Lee SC ; Brandt C ; Burke S ; Lu L ; He D ; Jenkins NA ; Copeland NG ; Dougan G ; Liu P J Exp Med 2015[Jun]; 212 (6 ): 865-74 PMID25964371 show ga Group 2 innate lymphoid cells (ILCs), or ILC2s, are a subset of recently identified ILCs, which play important roles in innate immunity by producing type 2 effector cytokines. Several transcription factors have been found to have critical functions in the development of both ILC2s and T cells. We report here that Bcl11b, a transcription factor essential in T cell lineage commitment and maintenance, is specifically expressed in progenitors committed to the ILC2 lineage and is required for ILC2 development. The Bcl11b gene is expressed in ?28% of ILC progenitors (ILCPs; common helper innate lymphoid progenitors or ILCPs expressing either ID2 or promyelocytic leukemia zinc finger, respectively). Both in vitro and in vivo, these Bcl11b-expressing early ILCPs generate only ILC2s. Inactivation of Bcl11b causes a complete loss of ILC2 development from hematopoietic progenitors, which is confirmed upon immune challenge with either papain administration or influenza virus infection. |*Gene Expression Regulation [MESH] |Animals [MESH] |Cell Lineage [MESH] |Cell Separation [MESH] |Chromatin Immunoprecipitation [MESH] |Female [MESH] |Flow Cytometry [MESH] |GATA3 Transcription Factor/metabolism [MESH] |Gene Deletion [MESH] |Gene Expression Profiling [MESH] |Genes, Reporter [MESH] |Hematopoietic Stem Cells/cytology [MESH] |Immunity, Innate [MESH] |Inducible T-Cell Co-Stimulator Protein/metabolism [MESH] |Interleukin-1 Receptor-Like 1 Protein [MESH] |Lymphocytes/*cytology/metabolism [MESH] |Male [MESH] |Mice [MESH] |Mice, Inbred C57BL [MESH] |Mice, Transgenic [MESH] |Receptors, Interleukin/metabolism [MESH] |Repressor Proteins/*metabolism [MESH] |Tumor Suppressor Proteins/*metabolism [MESH]The transcription factor Bcl11b is specifically expressed in group 2 i(epmc).pdf DeepDyve Pubget Overpricing